摘要
目的：评价异功散合玉屏风散加减治疗小儿肺炎支原体肺炎后期脾虚证的临床疗效。方法本研究为随机对照研究。将符合纳入标准静滴5 d阿奇霉素后出现脾虚证的60例患儿，按随机数字表法分为2组各30例。对照组继续口服阿奇霉素2周，治疗组在对照组基础上加用异功散合玉屏风散2周，观察症状积分改善情况判定疗效。结果治疗组食欲不振[（0.65±1.00）分比（2.32±1.28）分，t＝5.631]、食后腹胀[（0.73±0.23）分比（1.33±0.97）分，t＝3.297]、神疲懒言[（0.72±0.32）分比（1.42±1.18）分，t＝3.136]积分均较对照组降低（P均＜0.05）。治疗组肺炎支原体肺炎后期脾虚证疗效总有效率为90.0%（27/30），对照组为66.7%（20/30），2组比较差异有统计学意义（χ2＝4.812，P＜0.05）。结论异功散合玉屏风散加减可改善小儿肺炎支原体肺炎脾虚证的症状，促进疾病痊愈。
ObjectiveTo evaluate the clinical efficacy ofYigongpowder withYupingfengpowder for syndrome of spleen deficiency in children with mycoplasma pneumoniae pneumonia.MethodsA total of 60 patients who had spleen deficiency after azithromycin injection 5 days were randomly divided into treatment group and control group according to the random number table, with 30 in each group. The patients in both received azithromycin suspension for 2 weeks, while the patients in the treatment group received azithromycin suspension and traditional Chinese medicineYigongpowder withYupingfengpowder for 2 weeks. The symptoms score was used to evaluate the clinical efficacy.ResultsThe scores of appetite loss （0.65 ± 1.00vs. 2.32 ± 1.28,t=5.631）, abdominal distention （0.73 ± 0.23vs.1.33 ± 0.97,t=3.297） and fatigue （0.72 ± 0.32vs. 1.42 ± 1.18,t=3.136） in the treatment group were significantly lower than those in the control group （all P〈0.05）. The total effective rate for syndrome of spleen deficiency in the treatment group was significantly higher than thatin the control group（90.0%vs.66.7%;χ2=4.812,P〈0.05）.ConclusionYigongpowder withYupingfeng powder can significantly improve the symptoms of syndrome of spleen deficiency in children with mycoplasma pneumoniae pneumonia.
出处
《国际中医中药杂志》
2015年第6期498-501,共4页
International Journal of Traditional Chinese Medicine
基金
江苏省中医药局立项课题（LZ13098）
关键词
肺炎
支原体
肺炎支原体
叠氮红霉素
异功散
玉屏风散
脾虚
儿童
Pneumonia, mycoplasma
Mycoplasma pneumoniae
Azithromycin
Spleen deficiency
Yi Gong San
Yu Ping Feng San
Child
