摘要
目的了解血液病患者口腔假丝酵母菌感染现状,为制定医院感染防控措施提供参考。方法通过回顾性调查方式,对绍兴市人民医院血液科住院患者口腔假丝酵母菌感染情况进行调查。结果 2009-2013年共收治血液病患者6 719例,发生医院感染1 292例次,例次感染率19.2%。5年中共送检口腔白斑处棉拭子标本209例,检出口腔假丝酵母菌86例,检出率41.1%,感染率1.3%;口腔假丝酵母菌感染占全部医院感染的6.7%,感染率呈逐年增多趋势,发生口腔假丝酵母菌感染的血液病以急性白血病多见,感染菌种以白假丝酵母菌为主,占90.7%。结论应重视血液病患者口腔假丝酵母菌感染的预防和控制,规范化疗和糖皮质激素的使用疗程和剂量,对高危患者预先给予碳酸氢钠漱口液预防,以防止发生侵袭性真菌感染。
Objective To study the status of oral Candida mycoderma infection in patients with hematology disease, so as to provide guidance for infection prevention. Methods Retrospective survey was used to analyze the status of oral Candida mycoderma infection in hematology disease inpatients of Shaoxing People＇s Hospital. Results The nosocomial infection oc- curred in 1 292 of 6 719 inpatients with hematology disease from 2009 to 2013, the infection rate was 19.2%. 209 oral swab specimens were sent in 5 years, 86 cases （41.1%） of oral Candida mycoderma were detected out, the infection rate was 1.3%. Oral Candida mycoderma infections were 6.7% among total nosocomial infection, which showed a upward trend. The infection rate of oral Candida mycoderma was the highest in acute leukemia patients, and Monilia albicans was still the most frequent pathogeni. Using glucocorticoid, chemotherapy and without sodium bicarbonate solution were inde- pendent influencing factors of oral Candida mycoderma bacteria infection among hematology disease inpatients. Conclu- sion It is necessary to pay more attention to prevent and control oral Candida mycoderma infection in the patients with he- matology disease. The standard chemotherapy and glucocorticoid should be used. Sodium bicarbonate solution be taken to prevent in high risk patients.
出处
《中国消毒学杂志》
CAS
北大核心
2015年第6期556-558,共3页
Chinese Journal of Disinfection
关键词
血液病
口腔
假丝酵母菌
感染
hematology disease
oral
Candida mycoderma
infection
