摘要
甲状腺是人体重要的内分泌器官,其功能亢进或减退均会影响女性生育能力。甲状腺功能异常可影响女性血清促性腺激素和性激素水平。甲状腺激素可直接作用于卵巢,其过多或过少均可影响卵泡发育,损害卵巢储备力。甲状腺激素对输卵管功能的影响尚不明确。已有证据显示甲状腺激素可直接参与调节子宫内膜生理功能,影响子宫内膜容受性。甲状腺疾病可能影响宫腔对妊娠的承受能力,增加产科并发症和不良妊娠结局的发生。
Thyroid is as an important human endocrine organ and it＇s dysfunction can affect female fertility. Thyroid dysfunction can change gonadotropin and sex hormone levels in female serum. Thyroid hormones may also have a direct effect on the ovary, interfere with ovarian follicular development and impair ovarian reserve. The effects of thyroid hormones on the oviduct function is still not clear. However, there are evidences showing thyroid hormone receptor and thyroid stimulating hormone receptor in tubal tissues, suggesting that the oviduct is also one of the target of thyrod hormones. Evidences have also indicated that thyroid hormones can be directly involved in endometrial physiology and may affect endometrial receptivity. Thyroid diseases may also affect uterine bearing capacity during pregnancy and increase the incidence of obstetric complications and adverse pregnancy outcomes.
出处
《生殖与避孕》
CAS
CSCD
北大核心
2015年第5期339-344,共6页
Reproduction and Contraception
基金
上海市辅助生殖与优生重点实验室课题
课题编号:12DZ2260600
关键词
甲状腺
生育力
卵巢储备力
不孕
thyroid
fertility
ovarian reserve
infertility
