摘要
目的:应用超声实时三维斑点追踪技术(RT3D-STI)定量分析冠心病患者早期左心室节段收缩功能,探讨其在冠心病诊断中的应用价值。方法:搜集有胸闷、心绞痛病史,常规超声心动图未见室壁运动异常而经冠状动脉造影证实为冠心病的患者35例(冠心病组)及正常对照组21例,通过三维全容积图像获取左心室心肌收缩末期17节段"牛眼图",定量分析各节段收缩功能。结果:冠心病组缺血节段亚组与对照组、非缺血节段亚组比较,纵向应变(SLS)、圆击应变(SCS)、径向应变(SRS)、面积应变(SAS)差异均有统计学意义(P<0.05),而对照组与非缺血节段亚组间各参数比较差异均无统计学意义(P>0.05);应用ROC曲线分析表明SAS曲线下面积最大,且所有节段三维应变参数中以SAS>-26.5%检测缺血心肌节段的敏感度(83.3%)、特异度(80.3%)较好。结论:RT3D-STI可以定量评估冠心病早期左室节段收缩功能,SAS能很好地识别缺血心肌节段,在冠心病早期诊断中有较高的应用价值。
Objective：To assess the value of real-time 3D speckle tracking imaging echo cardiography （RT3D-STI） in quantitative analyze of early systolic function of left ventricle segments in patients with coronary heart disease. Methods： Thirty-five patients with a history of chest tightness, angina pectoris, no wall motion abnormalities shown by conventional ultrasound examination and coronary heart disease confirmed by coronary angiography were selected for our study as the disease group,and the other 21 healthy cases as the control group. 17 segments of ＂bovine eye chart＂ were obtained by full volume three dimensional images of left ventricle, and segmental systolic function was quantitatively analyzed. Results：In comparison of ischemic segments subgroup of coronary heart disease group with non-ischemic segments subgroup of control group,there were statistical significant difference of the absolute value of systolic longitudinal strains （SLS）, systolic cir- cumferential strains （SCS）,systolic radial strains （SRS） and systolic area strains （SAS） between ischemic segment sub- group of coronary heart disase group and the non-ischemic segment subgroup of control group （P〈0.05）. There was no significant difference of there parameters between the non-ischemic segment subgroup and the control group （P〉0.05）. The ROC curve analysis showed that SAS had the maximum of area under curve（AUC）,and SAS〉--26.5% for detection of myocardial ischemic segments had the highest specificity and sensitivity in all the three dimensional segmental strain pa- rameters. Conclusion：RT3D-STI can quantitatively evaluate the left ventricular segmental systolic function early in the coro- nary heart disease, and SAS has a higher value in the early diagnosis of coronary heart disease because of its better detection of myocardial ischemic segments.
出处
《放射学实践》
北大核心
2015年第5期599-602,共4页
Radiologic Practice
基金
广东省科学技术厅科技计划基金资助项目(2013A022100036)
关键词
实时三维斑点追踪技术
冠心病
收缩
超声检查
Real-time 3D speckle tracking imaging
Coronary disease
Constriction
Ultrasonography
