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简易吞咽激发试验在鼻咽癌放疗后吞咽障碍评估中的应用研究 被引量:9

Application of simple swallowing provocation test to evaluation of dysphagia in patients with nasopharyngeal carcinoma after radiotherapy
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摘要 目的探讨简易吞咽激发试验(simple swallowing provocation test,SSPT)对鼻咽癌放疗后吞咽障碍的诊断价值。方法 106例鼻咽癌患者放疗术后1年时分别采用SSPT、洼田饮水试验(kubota drinking test,KDT)及电视透视检查(videofluoroscopic swallowing study,VFSS)评定吞咽功能,以VFSS为金标准,分析SSPT、KDT与VFSS评估方法间的一致性及可靠性。结果 SSPT第一步诊断的灵敏度为72.41%,特异度为83.12%,阳性预测值为61.76%,阴性预测值为88.89%;SSPT第二步诊断的灵敏度为27.59%,特异度为98.70%,阳性预测值为88.89%,阴性预测值为78.35%;KDT的灵敏度为37.93%、特异度为80.52%,阳性预测值为42.31%,阴性预测值为77.50%;SSPT第一步、SSPT第二步、KDT与VFSS吞咽困难评分之间Kappa值分别为0.527、0.335和0.191。结论简易吞咽激发试验是评估鼻咽癌放疗后吞咽障碍的一个安全、方便且有价值的方法,值得临床推广。 Objective To study the diagnostic value of simple swallowing provocation test (SSPT) in evaluating dysphagia in patients with nasopharyngeal carcinoma (NPC) after radiotherapy. Methods 106 NPC patients underwent SSPT, Kubota drinking test (KDT) and videofluoroscopic swallowing study (VFSS) one year after radiotherapy. Taking VFSS as a golden standard evaluation method, consistency and reliability of SSPT were analyzed. Results The sensitivity, specificity, positive predictive value and negative predictive value of first-step SSPT for the detection of dysphagia were 72.41%, 83.12%, 61.76%, and 88.89% respectively. The indexes of second-step of SSPT were 27.59%, 98.70%, 88.89% and 78.35%, while those of KDT were 37.93%, 80.52%, 42.31% and 77.50%. Values of kappa between first-step SSPT, second-step SSPT, KDT and VFSS were 0. 527, 0. 335 and 0. 191 respectively. Conclusion SSPT is an effective and valuable method for evaluating dysphagia in NPC patients after radiotherapy.
出处 《中国耳鼻咽喉颅底外科杂志》 CAS 2015年第2期132-134,139,共4页 Chinese Journal of Otorhinolaryngology-skull Base Surgery
关键词 简易吞咽激发试验 洼田饮水试验 鼻咽癌 吞咽障碍 评估 Simple swallowing provocation test Kubota drinking test Nasopharyngeal neoplasm Dysphagia Evaluation
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