摘要
目的：了解郴州市第一人民医院药品不良反应（ADR）发生的特点及规律,促进临床合理用药。方法：收集该院2013年上报的350例ADR报告,按患者年龄、性别、给药途径、临床表现、所涉及的药品等进行统计分析。结果：350例ADR报告中,患者以40-60岁为主,女性较男性多;给药途径以静脉注射（占54.86%）居多;临床表现以皮肤及其附件损害最常见,占33.43%;ADR涉及药品172种,其中抗感染药引发的ADR最多,占31.14%。结论：临床应重视ADR的监测工作,加强对患者用药过程的观察,提高合理用药水平。
OBJECTIVE：To investigate the characteristics and regularity of the adverse drug reactions （ADRs） in Chenzhou First People＇s Hospital so as to promote clinical rational use of drugs. METHODS： 350 ADR reports collected from that hospital in 2013 were analyzed statistically in respects of patients＇ age, sex, routes of administration, clinical manifestation and types of causative drugs etc. RESULTS： Of the 350 ADR cases, ADR was more often seen in the patients aged 40-60 years, with female showing higher proportion than males; intravenous administration was the main route of administration, accounting for 54. 86% ; lesions of skin and its appendants were the main clinical manifestations, occupying 33.43% ; a total of 172 categories of drugs were involved, among which antibiotics took the lead （31.14%）. CONCLUSIONS： Great importance should be attached to monitoring of ADR and medication so as to improve the level of rational use of drugs.
出处
《中国医院用药评价与分析》
2015年第4期524-526,共3页
Evaluation and Analysis of Drug-use in Hospitals of China
关键词
药品不良反应
分析
合理用药
Adverse drug reaction （ADR）
Analysis
Rational use of drug
