摘要
目的探讨D-二聚体(D-D)、肌钙蛋白T(cTnT)及心肌酶谱检测在急性心肌梗死(AMI)临床诊断中的价值。方法选取AMI患者36例(AMI组)和体检健康者20例(健康对照组)作为研究对象,检测两组血浆D-D、cTnT、心肌酶谱水平及其灵敏度、特异度。结果 AMI组D-D、cTnT、肌酸激酶(CK)、肌酸激酶同工酶MB(CK-MB)、天门冬氨酸氨基转移酶(AST)、乳酸脱氢酶(LDH)水平均明显高于健康对照组,差异均有统计学意义(P<0.05)。AMI患者中,cTnT、D-D、心肌酶谱的阳性率分别为91.67%、69.44%、66.67%,cTnT阳性率明显高于D-D和心肌酶谱(P<0.05)。血浆cTnT对AMI的诊断灵敏度和特异度明显高于D-D和心肌酶谱(P<0.05)。结论与D-D和心肌酶谱相比,cTnT对AMI的诊断灵敏度和特异度更好,临床上可多项联合检测提高检测准确性。
Objective To investigate the value of D‐dimer （D‐D） ,cardiac troponin T（cTnT） and myocardial enzymogram detec‐tions in clinical diagnosis of acute myocardial infarction （AMI） .Methods 36 cases of AMI patients （AMI group） and 20 cases of healthy people （control group） were selected as study subjects .The plasma levels of D‐D ,cTnT and myocardial enzymogram of two groups were detected ,and the sensibility and specificity of these indexes were analyzed .Results The levels of D‐D ,cTnT ,CK ,CK‐MB ,AST and LDH in AMI group were significantly higher than those of control group （P〈0 .05） .The positive rates of cTnT ,D‐D and myocardial enzymogram in AMI patients were 91 .67% ,69 .44% ,and 66 .67% ,respectively .The positive rate of cTnT was significantly higher than those of D‐D and myocardial enzymogram （P〈0 .05） .Both of the diagnosis sensibility and specificity of plasma cTnT were significantly higher than those of D‐D and myocardial enzymogram （P〈0 .05） .Conclusion Comparing with D‐D and myocardial enzymogram ,plasma cTnT has better diagnosis sensibility and specificity .Joint detection of kinds of indexes could improve the accuracy .
出处
《国际检验医学杂志》
CAS
2015年第10期1325-1326,1329,共3页
International Journal of Laboratory Medicine
基金
广东省医学科研基金资助项目(B2012171)
关键词
肌钙蛋白T
心肌酶谱
D-二聚体
急性心肌梗死
cardiac troponin T
myocardial enzymogram
D-dimer
acute myocardial infarction
