摘要
目的:观察自拟养血消风汤辅治对慢性荨麻疹患者生活质量的影响及临床疗效。方法:将82例慢性荨麻疹患者随机分为治疗组及对照组,每组41例,对照组给予西药治疗,治疗组在对照组的基础上加用自拟养血消风汤治疗,两组均治疗4周;检测两组治疗前后的血清IL-4、IFN-γ及Ig E水平,记录患者治疗前后VAS评分、LFS评分及UAS评分,并比较治疗后1周、2周、4周的皮肤病生活质量指数评分(DLQI)以及疗效。结果:治疗后4周后,治疗组血清IL-4、Ig E水平低于对照组,IFN-γ高于对照组(P<0.05);治疗组治疗后4周的VAS评分、LFS评分、UAS评分均显著低于对照组(P<0.05);治疗组治疗后1周、2周、4周的DLQI评分均低于对照组(P<0.05);治疗后1周、2周、4周,治疗组的治疗总有效率均明显高于对照组(P<0.05)。结论:自拟养血消风汤辅治慢性荨麻疹有较好临床疗效,能够改善患者的免疫状态,提高患者的生活质量。
Objective： To observe influence of Yangxuexiaofeng Decoction （养血消风汤,YXXFF） on quality of life in pa- tients with chronic urticaria as well as therapeutic efficacy. Methods： The 82 cases of patients with chronic urticaria were ran- domly divided into treatment and control groups, 41 cases in each. Patients were treated by western medicine in control group, and YXXFT on the basis of control group in treatment group. The patients were treated for 4 weeks in two groups. The serum IL-4, IFN-γ and lgE levels were detected before and after treatment; VAS,LFS and UAS scores were recorded before and after treatment; dermatology life quality index score（DLQI） and therapeutic efficacy were also recoded before and after 1, 2 and 4 weeks. Results： The treatment showed lower serum IL-4 and lgE levels and higher IFN-γ level than the control group （P〈0.05） in 4 weeks; The treatment showed lower VAS score, LFS score and UAS score than the control group significantly in 4 weeks; DLQI score of treatment group was also lower than the control group after 1, 2 and 4 weeks treatment （P〈0.05）, and the total effective rate of treatment group was obviously higher than that of control group （P〈0.05）. Conclusion： YXXFT of adjuvant thera- py is effective in treatment of chronic urticaria, can obviously improve the patient＇s immune status and improve the quality of life of patients.
出处
《中医药导报》
2015年第11期19-22,共4页
Guiding Journal of Traditional Chinese Medicine and Pharmacy
基金
卫生部医药卫生研究科技发展研究中心项目(W2013GJ09)
关键词
荨麻疹
慢性
养血消风汤
生活质量
Urticaria
chronic disease
Yangxuexiaofeng Decoction （养血消风汤）
quality of life
