摘要
目的分析宣城市及其所辖区县2010年-2013年手足口病流行病学特征,为其防治提供科学依据。方法将送检的手足口病病例标本提取病毒核酸,将提取物通过real-time PCR的方法检测肠道病毒及其分型。结果共收集轻症手足口病标本1 388例,实验室检测轻症标本总阳性数为678例,其中EV71构成比为36.14%(245/678),Cox A16为20.21%(137/678),其他肠道病毒为43.66%(296/678)。轻重症及聚集性疫情标本EV71构成比差异有统计学意义(P<0.05)。结论引起宣城市手足口病病毒以其他肠道病毒居多;手足口病的发病有明显的年龄、季节差异;其中重症及聚集性疫情患儿中的手足口EV71病毒的检出率高于轻症患儿。
Objective To analyze the epidemiologic characteristics of hand - foot - mouth disease （HFMD） in Xuancheng and its presidial counties from 2010 to 2013 for providing scientific evidence of HFMD prevention. Methods Extract viral RNA of those samples isolated from HFMD cases, and the extraction was detected by real - time PCR to determine the intestinal tract vi- rus and the subtype. Results We collected 1 388 tracheal tract samples isolated from HFMD mild cases, among which 678 sam- ples were detected as positive. The constituent ratio of EV71 and CoxA16 were 36.14% （245/678） and 20.21% （137/678）, respectively, and the constituent ratio of other enterovirus was 43.66% （296/678）. Based on statistical analysis, the difference of constituent ratio of EV71 in HFMD cases of Xuancheng had statistical significance （ P 〈 0.05 ）. Conclusion The main in- centive of HFMD is other enterovirus; there are obvious differences among I-IFMD cases in several aspects, including age and seasonality; the detection rate of EV71 in severe cases and clustered epidemic is higher than that in mild cases.
出处
《中国卫生检验杂志》
CAS
2015年第9期1429-1431,共3页
Chinese Journal of Health Laboratory Technology
