摘要
目的探讨EB病毒抗体测定在儿童神经系统疾病诊断及治疗中的临床价值。方法从我院2012年3月至2014年3月收治的神经系统疾病患儿中选取110例为观察对象,随机分为观察组与对照组,每组55例,对照组采用聚合酶链式反应检测法,观察组采用免疫捕获法检测,对患儿抗NA-Ig G抗体、抗VCA-Ig M抗体、抗EA-Ig G抗体及抗VCA-Ig G抗体进行检测,观察其阳性情况,根据诊断结果,两组患儿均行针对性治疗,观察治疗效果。结果观察组患儿抗EBV-VCA-Ig M、抗VCAIg G、抗EA-Ig G、抗NA-Ig G阳性率均显著高于对照组患儿,差异具有统计学意义(P<0.05)。经治疗,观察组总有效率明显高于对照组,差异具有统计学意义(P<0.05)。结论在因EB病毒引起的儿童神经系统疾病的诊治中,采用免疫捕获法对4种抗体进行检测,具有较高的敏感性,可为患儿临床诊断及治疗提供重要参考,提高治疗质量。
Objective To explore the clinical value of EB virus antibody detection in diagnosis and treatment of children with nervous system disease. Methods 110 children with nervous system disease in our hospital from March 2012 to March 2014 were selected and randomly divided into two groups, with 55 cases in each group. The positive rate of anti-NA-IgG antibody, anti-VCA-IgM antibody, anti-EA-IgG antibody and anti-VCA-IgG antibody of control group （polymerase chain reaction） and observation group （immunocaptured technique） were detected. According to the results, all cases were given targeted treatment, and the curative effects of two groups were compared. Results The positive rates of anti-NA-IgG antibody, anti-VCA-IgM antibody, anti-EA-IgG antibody and anti-VCA-IgG antibody of observation group were significantly higher than those of control group （P 〈0.05）. After treatment, the total effective rate of observation group was significantly higher than that of control group （P 〈0.05）. Conclusions In diagnosis of EB-related nervous system diseases in children, immunocaptured technique has high sensitivity to detect four kinds of antibody, so as to provide reference for diagnosis and treatment in clinic, and improve curative quality.
出处
《临床医学工程》
2015年第5期586-587,共2页
Clinical Medicine & Engineering
关键词
EB病毒
神经系统疾病
诊断
治疗
EB virus
Nervous system disease
Diagnosis
Treatment
