摘要
In the past few years, we have witnessed and been excited by biotechnological advances that allow for the precise editing of genomic information in living eukaryotic cells. Facilitated by TALEN (transcription activator-like effector nucleases) or CRISPR (clustered regularly interspaced short palindromic repeats) systems, scientists can now routinely perform gene-editing in a variety of organisms including plants, insects, rodents and primates, as well as in human somatic cells in basic research. These innovative techniques have opened up new opportunities for scientific discovery and human disease therapeutic development that were not possible just a few years ago. Recently, scientists try to apply the gene-editing techniques to human germ cells and embryos,
In the past few years, we have witnessed and been excited by biotechnological advances that allow for the precise editing of genomic information in living eukaryotic cells. Facilitated by TALEN (transcription activator-like effector nucleases) or CRISPR (clustered regularly interspaced short palindromic repeats) systems, scientists can now routinely perform gene-editing in a variety of organisms including plants, insects, rodents and primates, as well as in human somatic cells in basic research. These innovative techniques have opened up new opportunities for scientific discovery and human disease therapeutic development that were not possible just a few years ago. Recently, scientists try to apply the gene-editing techniques to human germ cells and embryos,