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CD73在骨代谢中作用的研究进展 被引量:1

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摘要 先天性胫骨假关节(CPT)是由于骨发育异常所致的胫骨畸形和特殊类型的骨折不愈合[1]。而实现胫骨假关节的骨性愈合和维持骨性连接则是治疗CPT 的关键。虽然目前有很多该病治疗方法的报道,使该病的治愈率得到很大改观,但其治愈率仍存在很大差异[2]。手术方法的改进虽提高了 CPT 的治愈率,但仍存在治疗失败,如假关节不愈合,骨性连接不稳定,甚至导致截肢的可能。该病的骨延迟愈合或不愈合是否与成骨因素缺陷有关仍是未知。骨愈合是一个复杂而精细的多级再生过程,成骨细胞是骨形成的主要功能细胞,在骨重塑中起着重要的作用。
出处 《临床小儿外科杂志》 CAS 2015年第2期145-147,共3页 Journal of Clinical Pediatric Surgery
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