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Th17细胞在妇产科疾病中作用研究进展 被引量:3

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摘要 T淋巴细胞是人体内免疫系统的重要组成部分,CD4+T细胞作为效应T细胞的重要成员之一,过去将CD4+T细胞分为Th1和Th2两类细胞亚群[1]。Th1细胞主要介导细胞免疫,主要分泌白细胞介素2(IL-2)、肿瘤坏死因子β(TNF-β)、干扰素γ(IFN-γ)等。其中IFN-γ占主导地位,具有诱导肿瘤细胞凋亡、抑制血管生成,激活抗肿瘤活性的作用。尤其是在细菌、病毒及原虫感染中起保护作用[2]。Th2细胞主要分泌IL-4、IL-5、IL-10和IL-13,介导体液免疫反应。其中IL-4和IL-5起主要作用,
作者 袁芳 杨兴升
出处 《中国实用妇科与产科杂志》 CAS CSCD 北大核心 2015年第5期473-475,共3页 Chinese Journal of Practical Gynecology and Obstetrics
关键词 TH17细胞 CD4+T细胞亚群 白细胞介素-17 妇产科疾病 Th17 cell CD4+T cell subset interleukin-17 obstetrical and gynecological diseases
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参考文献19

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