摘要
目的探讨入院后1h内做胃镜检查及镜下治疗,同时使用强效质子泵抑制剂(PPI)对抢救急性上消化道出血的应用价值。方法选择我院2013年救治的入院考虑上消化道出血即在1h内做胃镜同时使用强效PPI的上消化道出血患者133例作为研究组,选择2012年采取常规急诊救治方法进行急救的上消化道出血患者110例作为对照组。结果研究组患者通过急诊胃镜救治后,病死率为0.75%,低于对照组的4.55%(P<0.05);研究组输血量(293.63±46.95)ml、住院时间(7.50±1.27)d、住院费用(6805.52±375.41)元,也均少于对照组的(439.38±33.71)ml、(10.45±1.93)d、(7475.64±340.42)元(P<0.001)。结论早期使用急诊胃镜加强效PPI对上消化出血患者实施急诊治疗,可有效提高患者临床治愈率,促进患者健康恢复。
Objective To evaluate the value of emergency gastroscopy/endoscopic therapy within an hour after admission combined with superactive proton pump inhibitor （PPI）in saving patients with acute upper gas-trointestinal tract hemorrhage. Methods Acute upper gastrointestinal tract hemorrhage patients cared at our hospital were divided into an experimental group （133 cases in 2013）and a control group （1 10 cases in 2012）. The experimental group was treated with emergency gastroscopy/endoscopic therapy within an hour after ad-mission combined with superactive proton pump inhibitor （PPI）.The control group was treated with tradition-al emergency management. Results The mortality rate in the experimental group after endoscopic therapy was 0.75% and lower than that in the control group （4.55%）（P 〈0.05）.The volume of blood transfusion, hospitalization duration and hospitalization cost in the experimental group were significantly lower than those in the control group[（293.63 ± 46.95）ml versus （439.38 ± 33.71）ml,（7.50 ± 1.27）days versus （10.45 ± 1.93）days,（6805.52 ± 375.41）yuan versus （7475.64±340.42）yuan,respectively,and P 〈0.001]. Con-clusion Early use of emergency gastroscopy/endoscopic therapy combined with superactive PPI therapy could effectively improve the clinical cure rate and facilitate the recovery in patients with acute upper gastrointestinal tract hemorrhage.
出处
《右江民族医学院学报》
2015年第2期204-205,共2页
Journal of Youjiang Medical University for Nationalities
关键词
上消化道出血
急诊胃镜
强效
PPI
upper gastrointestinal hemorrhage
emergency gastroscopy
superactive proton pump inhibi-tor
