摘要
目的探讨术前三维适形放疗同步化疗对Ⅲ期非小细胞肺癌(NSCLC)病人预后的影响。方法以2007—2010年我院收治的术前行三维适形放疗同步化疗的Ⅲ期非小细胞肺癌病人49例作为观察组,直接手术病人47例作为对照组。比较两组手术切除率、术后并发症发生率及术后生存率的差异。结果观察组手术切除率显著高于对照组(χ2=4.304,P<0.05)。两组术后并发症发生率差异无显著性(P>0.05)。观察组1、3年生存率显著高于对照组(χ2=4.221、4.200,P<0.05)。结论术前三维适形放疗同步化疗可以显著提高Ⅲ期非小细胞肺癌的手术切除率及病人1、3年生存率,对术后并发症发生率无明显影响。
Objective To assess the effect of preoperative three dimensional conformal radiotherapy combined chemo-therapy （combined therapy） on the prognosis of patients with stage Ⅲ non-small cell lung cancer （NSCLC）. Methods Forty-nine patients with stage Ⅲ NSCLC treated with the combined therapy before surgery during 2007--2010 were selected as observation group, and 47 underwent surgery without preoperative combined therapy served as a control group. A comparison was made between the two groups in terms of resection rate, post-operative complications and post-operative survival. Results The resection rate in the observation group was higher than that in the control grou （X 2 = 4.304, P ~0.05）. The post-operative complications were not significantly different between the two groups （P〉0.05）. The one-year and three-year survival rates were higher in the observation group than the control group （X 2= 4.221,4. 200 ; P〈0.05）. Conclusion Preoperative three dimensional conformal radiotherapy combined chemotherapy can significantly increase the resection rate, one-and three-year survival rates of patients with stage Ⅲ NSCLC, which does not affect post-operative complications.
出处
《齐鲁医学杂志》
2015年第2期147-148,151,共3页
Medical Journal of Qilu
关键词
癌
非小细胞肺
放射疗法
适形
药物疗法
预后
carcinoma, non-small-cell lung
radiotherapy, conformal
drag therapy
prognosis
