摘要
目的探讨血液透析病人系统性炎症反应状况及其对生存影响。方法收集119例血液透析病人（生存组96例,死亡组23例;NYHA分级1~2级64例,3~4级55例）,对其血常规、生化指标、超敏C反应蛋白和肌钙蛋白进行分析。结果生存组与死亡组血清蛋白、胆固醇、超敏C反应蛋白、肌钙蛋白水平相比较,差异有统计学意义（t=2.11~14.69,P〈0.05）。不同心功能组血清蛋白、超敏C反应蛋白、肌钙蛋白、血红蛋白水平相比较,差异有统计学意义（t=2.40~9.50,P〈0.05）。单因素Logistic回归分析显示,死亡与超敏C反应蛋白、肌钙蛋白、清蛋白和胆固醇水平有关,差异有统计学意义（χ2=4.26~30.05,P〈0.05）。结论系统性炎症反应对血液透析病人的生存有重要影响。
Objective To investigate the systemic inflammatory reaction in patients undergoing hemodialysis and its im pact on their survival. Methods Data of 119 hemodialysis patients were collected, of whom, 96 survived, and 23 died. NYHA grading： grade 1--2, 64 cases, and grades 3--4, 55 cases. An analysis was done with regard to the blood routine, biochemical indi- cators, supersensitive C-reactive protein （SSCRP） and cardiac troponin. Results Differences between the survival and death group were statistically significant in terms of levels of serum albumin, cholesterol, SSCRP and cardiac troponin （t ： 2.11-14.69, P〈0.05）, the differences of that between different group with different cardiac function were also significant （t=2.40--9.50, P〈0.05）. A univariate Logistic regression analyses showed death was associated with the levels of SSCRP, cardiac troponin, and se- rum albumin cholesterol X^2=4.26--30.05,P〈0.05）. Conclusion Systemic inflammatory reaction plays an important role in survival of patients undergoing hemodialysis.
出处
《青岛大学医学院学报》
CAS
2015年第2期202-204,共3页
Acta Academiae Medicinae Qingdao Universitatis
关键词
C反应蛋白质
肌钙蛋白
肾透析
无病生存
C-reactive protein
troponin
renal dialysis
disease-free survival
