摘要
目的:客观评价针刺对绝经过渡期(MT)绝经相关症状的疗效以及针感得气对疗效的影响。方法:将90例患者随机分配到针刺组(30例)、安慰针组(30例)和穴位浅刺组(30例)。采用平均24h烘热积分、绝经症状评价量表(MRS)作为主要评价指标进行评价。结果:13组患者的平均24h烘热积分、MRS量表得分经多元方差分析,组间差异均有统计学意义(P<0.05)。23组患者平均24h烘热积分各时点两两比较的结果显示,针刺组与穴位浅刺组比较,差异无统计学意义;针刺组、穴位浅刺组分别与安慰针组比较,差异均有统计学意义(P<0.05)。33组患者MRS量表各时点两两比较,治疗第4周,针刺组与安慰针组比较,差异有统计学意义(P<0.05),穴位浅刺组分别与针刺组、安慰针组比较,差异均无统计学意义;其余各时点两两比较均有统计学差异(P<0.05),其中针刺组降分幅度最大,浅刺组次之,安慰针组最小。结论:针刺治疗MT绝经相关症状是一种有效安全的方法;针刺得气与否可影响针刺的疗效。
Objective: To assess curative effect of acupuncture and Deqi on the treatment of menopause-related symptoms of menopause transition. Methods: Ninty patients were randomly divided into three groups: acupuncture group (30 patients), sham acupuncture group (30 patients) and shallow acupuncture group (30 patients). 24h hot flush scores and menopause rating scale questionnaires(MRS) were used to measure the outcomes. Results: (1)Variance analysis of hot flush scores and MRS scores showed significant differences between the groups (P〈0.05). (2)For hot flush scores, multiple comparisons did not show differences between acupuncture group and shallow acupuncture group; Both acupuncture group and shallow acupuncture group had significant differences to sham acupuncture group. (3)For MRS scores, differences in every two groups were significant (P〈0.05), acupuncture group decreased the most, followed with the shallow group and sham group. Conclusion: Analysis results of the trial indicated that acupuncture is safe and has effective on menopause-related symptoms of menopause transition, and Deqi could affect the efficacy of acupuncture in the treatment of menopause transition
出处
《中华中医药杂志》
CAS
CSCD
北大核心
2015年第5期1752-1756,共5页
China Journal of Traditional Chinese Medicine and Pharmacy
基金
"十二五"国家科技支撑计划项目(No.2012BAI24B01)
国家自然科学基金项目(No.81173348)~~