摘要
目的探讨单侧与双侧椎弓根入路经皮穿刺椎体成形术(PVP)治疗骨质疏松性椎体压缩性骨折(OVCFs)的临床疗效及价值。方法对2007年4月—2014年2月大连大学附属新华医院骨科65例获得6个月以上随访的骨质疏松性单个椎体压缩性骨折的临床病例进行回顾性研究,其中采用单侧椎弓根入路经皮穿刺椎体成形术治疗36例,双侧椎弓根入路经皮穿刺椎体成形术治疗29例,观察术后疼痛缓解、脊柱功能恢复及并发症发生情况,比较两组患者手术时间、骨水泥填充量、X线照射次数及术后VAS(视觉模拟疼痛)评分。结果单侧组手术时间(25±6)min明显少于双侧组(45±5)min,差异有显著性意义(P<0.05)。单侧组骨水泥渗漏率8.3%,与双侧组6.9%比较差异无显著性意义(P>0.05)。单侧组术中X线曝光(10.5±2.5)次,明显少于双侧组(19.4±3.0)次,差异有显著性意义(P<0.001)。两组术后24 h、术后6、12个月VAS评分比较无明显差异(P>0.05)。结论单侧经皮椎体成形术治疗骨质疏松性压缩性骨折具有手术时间短、患者在术中进行X线照射次数少,费用低等优点,可作为治疗骨质疏松性压缩性骨折的首选方法。
Objective To compare the clinical efficacy of unilateral versus bilateral percutaneous vertebroplasty （PVP） in the treatment of osteoporotic vertebral fractures （OVCFs）. Methods A retrospective study was carried out on 65 patients with osteoporotic vertebral compression fractures from April 2007 to February 2014 at the department of orthopaedics of the Xinhua Hospital affiliated of Dalian University. Patients were assigned to two groups and received unilateral （36 eases） or bilateral （29 cases） PVP treatment under local anesthesia. The operative time, amount of bone cement injected, frequency of X - ray exposure and postoperative VAS score were compared. Results The unilateral group had an average operative time of （ 25 ±6 ） min, which was significantly shorter than that of bilateral group （45 ±5 ） min （ P = 0.011 ）. The leakage rate of bone cement was 8.3% （3/36） in the unilateral group and 6.9% （2/29） in the bilateral group. There was no significant difference between the two groups （ P 〉 0.05 ）. The X - ray exposure frequency in the unilateral group was （ 10.5 ＋ 2.5 ） times,which was significantly less than that in the bilateral group （ 19.±＋ 3.0） times （ P 〈 0. 001 ）. No statistical difference could be found in VAS assessment 24 h,6 months, and 12 months after the surgery between the two groups （P 〉 0.05）. Conclusion Unilateral PVP can be used as preferred method for the treatment of OVCFs due to the advantages of shorter operation time,less X -ray exposure frequency and low cost.
出处
《大连医科大学学报》
CAS
2015年第2期145-147,168,共4页
Journal of Dalian Medical University
基金
大连市医学卫生科学研究计划项目(2010)
关键词
骨质疏松
椎体压缩性骨折
经皮椎体成形术
osteoporosis
vertebral compression fractures
percutaneous vertebroplasty （PVP）
