摘要
目的：观察重组人表皮生长因子对肛周脓肿患者术后创面愈合的影响。方法随机将112例肛周脓肿手术患者分为治疗组（ n＝56）和对照组（ n＝56）。治疗组：创面用生理盐水消毒，以浸有重组人表皮生长因子凝胶纱条填塞。对照组：常规消毒，用甲硝唑纱条或雷佛奴尔纱条填塞。手术后3、7、10 d观察创面水肿情况及愈合时间。结果治疗组和对照组手术后3、7、10 d创面水肿评分分别为[（1.20±0.70）、（1.00±0.67）、（1.05±0.69）]和[（1.70±0.66）、（1.90±0.74）、（1.70±0.73）]，两组比较差异有统计学意义（ P﹤0.05），两组创面愈合时间比较，差异有统计学意义（ P﹤0.05）。结论重组人表皮生长因子能明显促进创面愈合。
Objective To observe the effects of recombinant human epidermal growth factor （ rhEGF）on wound healing of perianal abscess after operation. Methods A total of 112 cases of perianal abscess after operation were randomly divided into the study group（ n=56 ）and control group（ n=56 ）. Patients in the control group were disinfected routinely and treated by metronidazole or rivanol. In the stud-y group,patients were treated by rhEGF after disinfection of saline. Wound edema score was evaluated at the 3rd,7th and 10th day after the surgery. Healing time of the wound was recorded simultaneously. Re-sults Wound edema scores in the study group[（1. 20 ± 0. 70）,（1. 00 ± 0. 67）,and（1. 05 ± 0. 69）] were significantly lower than those of the control group[（1. 70 ± 0. 66）,（1. 90 ± 0. 74）,and（1. 70 ± 0. 73）]at the 3rd,7th and 10th day after operation（P﹤0. 05）. Conclusion rhEGF can promote wound healing obviously.
出处
《临床外科杂志》
2015年第4期286-287,共2页
Journal of Clinical Surgery
关键词
表皮生长因子
脓肿
创面愈合
epidermal growth factor
abscess
wound healing
