摘要
目的 探讨过度充填对兔下颌髁突软骨的影响。方法 18只 5月龄纯种新西兰兔 ,等分为空白对照组、实验Ⅰ组 (单次充填组 )、实验Ⅱ组 (多次充填组 )。实验组一侧上颌第一前磨牙和对侧下颌第一前磨牙制洞 ,采用光固化树脂过度充填 ,造成与对颌牙的急性牙合干扰 ,2月后取双侧颞下颌关节 ,组织切片 ,HE染色 ,计量组织学分析。结果 多次充填组髁突软骨出现明显退行性病变 ,髁突前中部软骨层次紊乱 ,纤维带、增殖带和肥大带变薄 ,单次充填组程度相对较轻。结论 过度充填所致的咬合干扰可导致髁突软骨发生退行性病变 。
Objective To investigate the effects of premolars hyper-filling on the rabbit temporomandibular joint . Methods 18 five-month-old male New Zealand rabbits were divided into randomly normal control group.2-month-mono-group and 2-month-multi-group. Cavity preparation and filling with light-curing composite in first premolars one each random side ,upper and lower,resulted in immediate occlusal disturbance.Two months after treatment ,TMJs were harvested and sections were stained with haematoxylin and eosin .The stained sections were studied by light microscope and histometric analysis . Results Compared with normal control group,obvious degenerative changes were found in condylar cartilage of 2-month-multi-group.Most demarcation of layers became unclear. The average thicknessof fibrous layer,proliferative layer,hypertrophic layer and whole cartilage tissue decreased significantly in the anterior and center parts of condyles.However, light similar change showed in the 2-month-mono-group. Conclusion The occlusal disturbance resulted from hyper-filling in premolars may lead to degenerative changes of rabbit condyle.
出处
《临床口腔医学杂志》
2002年第4期250-252,共3页
Journal of Clinical Stomatology
基金
高等学校骨干教师资助计划资助