摘要
目的：探讨左旋氨氯地平、氨氯地平在高血压中的治疗效果。方法选取2012年5月~2014年1月我院收治的高血压患者共115例，并随机分为对照组（n=57）和观察组（n=58）。对照组给予苯磺酸氨氯地平片治疗，观察组给予苯磺酸左旋氨氯地平片治疗，对比两组的血压变化情况、治疗疗效和不良反应。结果治疗后，对照组、观察组SBP和DBP水平相比，差异无统计学意义（t=0.378，P=0.706；t=0.187，P=0.352）；观察组高血压治疗有效率为84.5%，与对照组80.7%相比，差异无统计学意义（χ2=0.286，P=0.593）；观察组不良反应率为5.2%，显著低于对照组的21.1%（χ2=6.392，P=0.012）。结论左旋氨氯地平、氨氯地平治疗高血压的效果类似，但左旋氨氯地平的不良反应更低，安全性更高。
Objective To investigate effect of levamlodipine and amlodipine in treatment of hypertension. Methods A total of 115 cases of hypertension from May 2012 to January 2014 in our hospital were collected, and were randomly divided into control group （n=57） and observation group （n=58）. The control group was given amlodipine besylate tablets treatment, while the observation group was given levamlodipine besylate tablets treatment. Adverse reaction, the change of blood pressure, the total curative effect of two groups were compared. Results After treatment, SBP and DBP levels of control group and the observation group had no significant difference （t=0.378, P=0.706; t=0.187, P=0.352）. The effective rate of observation group was 84.5%, while the control group was 80.7%, and there was no significant dif-ference between two groups （χ2=0.286, P=0.593）. The adverse rate of observation group was 5.2%, which was lower than that of control group 21.1%（χ2=6.392, P=0.012）. Conclusion Levamlodipine and amlodipine has a similar treatment ef-fect for hypertension, but the levamlodipine has lower adverse reaction and higher security.
出处
《中国现代医生》
2015年第11期102-104,共3页
China Modern Doctor
