摘要
目的：探讨女性妊娠期血脂变化与妊娠高血压综合征（ pregnancy-induced hypertension syn-drome，PIHS）的相关性。方法选取重庆市沙坪坝区妇幼保健院2010年9月至2013年9月收治的103例PIHS产妇，纳入PIHS组，并选取同期妊娠期非高血压产妇及未妊娠妇女各100例，并纳入对照组及正常组，比较各组受试者血脂检测指标。结果轻度PIHS患者血清总胆固醇（TC）、甘油三酯（TG）、低密度脂蛋白胆固醇（LDL-C）、载脂蛋白B（ApoB）及脂蛋白（a）【LP（a）】显著低于重度PIHS患者，其高密度脂蛋白胆固醇（HDL-C）、载脂蛋白A1（ApoAI）显著高于后者（P＜0.05）；PIHS组TC、TG、LDL-C、ApoB、LP （a）均显著高于对照组及正常组（P＜0.05），PIHS组HDL-C、ApoAI水平亦显著高于正常组，但低于对照组（P＜0.05），此外，对照组各项血脂检测指标亦显著高于正常组（P＜0.05）。结论在今后的检查中，应重点关注HDL-C、ApoAI 2项血脂指标，做到PIHS的早发现、早治疗，改善母婴结局。
Objective To investigate the correlation between changes of blood lipid in pregnant women and pregnancy induced hypertension syndrome （ PIHS） .Methods 103 cases with PIHS admitted from Sep .2010 to Sep.2013 were the PIHS group, 100 cases of pregnant women without hypertension were the control group , and 100 cases of non-pregnant women were the normal group .The blood lipids of each group were detected .Re-sults Total cholesterol（TC）, triglyceride（TG）, low density lipoprotein cholesterol （LDL-C）, apolipoprotein b （ApoB）and lipoprotein-a[LP（a）]were significantly lower while high-density lipoprotein cholesterol（HDL-C）and apolipoprotein a1（ ApoAI） were significantly higher in patients with mild PIHS than in patients with severe PIHS （P〈0.05）.TC, TG, LDL-C, ApoB, and LP（a）were significantly higher in PIHS group than in the normal group and the control group（P〈0.05）.HDL-C and ApoAI levels in PIHS group were significantly higher than those in the normal group, but lower than those in the control group （P〈0.05）.In addition, normal blood lipid indexes were significantly higher in the control group than in the normal group （ P〈0.05 ） .Conclusion We should pay more attention to HDL-C and ApoAI in order to accomplish the goal of early discovery and early treat-ment of PIHS, improving maternal and neonatal outcomes .
出处
《中华内分泌外科杂志》
CAS
2015年第2期164-166,共3页
Chinese Journal of Endocrine Surgery
关键词
妊娠
血脂
妊娠高血压综合征
Pregnancy
Blood lipid
Pregnancy induced hypertension syndrome
