摘要
目的：与传统方法比较评价辐照氟银猪皮覆盖创伤创面的疗效。方法：大面积皮肤撕脱伤创面（Ａ组）经积极抗休克、血压稳定后覆盖辐照氟银猪皮，小面积皮肤撕脱伤创面（Ｂ组）和肉芽创面（Ｄ组），邮票植皮后再用辐照氟银猪皮覆盖；感染创面（Ｃ组）经反复清洗后用辐照氟银猪皮覆盖。结果：体外抑菌试验表明，辐照氟银猪皮有很强的抑菌作用，Ａ组创面渗出少，疼痛减轻，Ｂ组创面９±１．４３ｄ愈合，Ｄ组创面１２±１．３ｄ愈合，Ｃ组创面与猪皮平均粘附１０±２．５５ｄ，肉芽新鲜。结论：辐照氟银猪皮能减少创面液体、蛋白质、电解质渗出，减少热量散失，从而减轻严重创伤后的超高代谢，促进肉芽和上皮生长，防治创面感染。
bjective:To compare the effects of radiated pig skin impregnated with Nofloxacin and silver (RPSINS) on wound healing with those of the traditional way.Methods:RPSINS was used to cover: the surface of large area of denuded skin after the patients recovered from shock and the arterial pressure became stable (group A); small area of denuded skin (group B) and granulation surface (group D) after stamp dermoplasty;infected wound (group C) after having been cleaned repeatedly.Results:The RPSINS was proved to have good antibacterial effect from experiments.It reduced exudation, lessened pain in group A; the wound surface was healed in 9±1.43 days in group B, in 12±1.3 days in group C;In group C PRSINS adhered to the wound for 10±2.55 days and the granulation tissue was fresh. Conclusion: RPSINS can reduce fluid and protein loss, maintain adequate electrolyte balance and reduce heat loss, hence it lessens superhigh metabolism after severe injury. It also promotes granulation and epithelial growth as well as protects the wound surface from infection.
出处
《江西医学院学报》
1998年第1期33-36,共4页
Acta Academiae Medicinae Jiangxi
关键词
辐照氟银猪皮
创伤
皮肤缺损
临床应用
radiated pig skin impregnated with Nofloxacin and silver△/therapeutic use
wounds and injuries/surgery
skin/injuries
