摘要
目的探讨尼莫地平注射液联合6-氨基己酸在蛛网膜下腔出血中的应用效果。方法选取2012年5月—2014年7月赫章县人民医院收治的蛛网膜下腔出血患者50例,将患者随机分为对照组与治疗组,每组25例。对照组单独使用尼莫地平注射液治疗,治疗组应用尼莫地平注射液联合6-氨基己酸治疗,比较两组临床疗效、格拉斯哥预后量表(GOS)评分与并发症发生情况。结果治疗组总有效率(92.00%)高于对照组(64.00%),再出血发生率(16.0%)低于对照组(32.0%),差异有统计学意义(P<0.05)。观察组患者GOS评分高于对照组,差异有统计学意义(P<0.05)。结论尼莫地平注射液联合6-氨基己酸治疗蛛网膜下腔出血临床效果好,可显著降低再出血发生率,改善患者预后。
Objective To explore the application effect of Nimodipine Injection combined with 6-aminocaproic acid on subarachnoid hemorrhage. Methods In People＇s Hospital of Hezhang from May 2012 to July 2014,50 subarachnoid hemorrhage patients were selected,they were randomly divided into control group and treatment group,25 cases in each group. The control group was treated with Nimodipine Injection,the treatment group was treated with Nimodipine Injection combined with 6-aminocaproic acid,the curative effect,Glasgow Outcome Scale（ GOS） score and complications of two groups were compared. Results The total effective rate of treatment group（ 92%） was higher than that of control group（ 64%）,rebleeding rate（ 16%） was lower than that of control group（ 32%）,the differences were statistically significant（ P 0. 05）,GOS scores of treatment group were higher than control group,the difference was statistically significant（ P 0. 05）. Conclusion Nimodipine Injection combined with 6-aminocaproic acid has good clinical effect in the treatment of subarachnoid hemorrhage,can significantly reduce the rebleeding rate and improve the prognosis of patients.
出处
《临床合理用药杂志》
2015年第12期50-51,共2页
Chinese Journal of Clinical Rational Drug Use
