摘要
目的了解贵州省镇宁县健康人群乙型肝炎病毒表面抗体（抗-HBs）水平,为降低人群乙肝感染率及制定相应防制措施提供一定依据。方法 2013年采集镇宁县15个乡（镇）〈1岁,1-2岁,3-4岁,5-6岁,7-9岁,10-14岁,15-19岁,≥20岁8个年龄组健康人群血清标本360份,采用酶联免疫吸附试验检测抗-HBs。结果抗-HBs检测360份,抗-HBs阳性181份,阳性率50.28%;不同年龄组间抗-HBs阳性率差异有统计学意义（χ^2=24.88,P〈0.01）;男女性别间抗-HBs阳性率差异无统计学意义（χ^2=0.10,P〉0.05）;各乡（镇）间抗-HBs阳性率差异有统计学意义（χ^2=50.26,P〈0.01）。结论镇宁县健康人群抗-HBs水平较低,应针对性地采取措施,提高免疫成功率。
Objective To understand the immunity level of hepatitis HBs Ab in healthy population in Zhenning county of Guizhou and provide evidence to reduce infection rate and to formulate preventive control measures. Methods Altogether 360 serum samples were collected from healthy population among 15 towns in Zhenning county,and Enzyme linked immunosorbent assay（ ELISA） was conducted to detect the HBs Ab. Results Of the 360 cases,181 were HBs Ab positive（ 50. 28%）. There were also statistical differences within age groups in the positive rates（ χ^2= 24. 88,P 〈0. 01）. No statistical gender differences was exhibited in the positive rate of anti-HBs Ab（ χ^2= 0. 10,P 〈0. 05）. While statistical significance was found among the towns in terms of HBs Ab positive rate（ χ^2= 50. 26,P〈0. 01）. Conclusion The level of HBs Ab antibody is low in the health population of Zhenning. Therefore,pertinent countermeasures should be taken to elevate the success rate of immunization.
出处
《职业卫生与病伤》
2015年第2期94-96,共3页
Occupational Health and Damage
关键词
健康人群
乙型肝炎
抗体
监测
healthy people
hepatitis B
antibody
surveillance
