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自体骨髓经皮注射移植治疗骨不连和骨延迟愈合的临床应用观察 被引量:3

The Clinical Observation of Percutaneous Autogenous Bone Marrow Injection Grafting For Treatment of the Delayed Union or Nonunion of Fractures
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摘要 目的应用自体骨髓经皮注射移植的方法治疗骨不连和骨折延迟愈合,并观察其治疗效果。方法2001至2011年,选择不同部位骨不连、骨折延迟愈合患者36例,在无菌条件下行自体髂骨骨髓穿刺抽吸,x线引导下,经皮注射移植到患部,并配合外固定等治疗。每部位注射2~3次,平均2.4次。每3~4周注射1次。结果术后平均随访患者9个月。36例患者中,32例治愈,4例失败而选择其他治疗方法。无感染及并发症发生。结论自体骨髓经皮注射移植是一种效果确切、简便易行、省钱微创、尤其在患者全身或局部条件不宜复杂操作时更彰显优势的治疗骨不连和骨折迟缓愈合的实用治疗方法。 Objective To observe the application of percutaneous autogenous bone marrow injection graft- ing for management of 36 cases with delayed union or nonunion of fractures. Methods In the period from 2001 to 2011, 36 patients with delayed and non - union of long bones were selected for bone marrow injection. Theprocedures were done in the operative theatre in which the bone marrow were aspirated from the anterior or pos- terior iliac crest and injected into the fracture site under fluoroscopic control. At a dose of 5-20 ml the optimal injection interval was 3-4 weeks and the injection required 2-3 times. Results During a mean follow up of 9 months, 32 of the 36 cases healed with the technique of marrow injection. The time to clinical and roentgen graphic union was 6-11 months after injection (averaged 9 months). 4 cases failed to choose other treatments, no infection and complications. Conclusion Bone marrow injection is as effective as past open autologous graft- ing but with considerably fewer disadvantages and also it is a relatively simple technique, especially for elderly and infirm patients.
出处 《内蒙古医学杂志》 2015年第4期401-403,共3页 Inner Mongolia Medical Journal
关键词 骨不连 自体 骨髓移植 ununited autogenous bone marrow transplantation
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