摘要
目的:探讨乌司他丁辅助治疗急性肺损伤病人的临床疗效。方法:将80例急性肺损伤病人采用数字表格方法随机分组为对照组(40例)和观察组(40例)两组。对照组采用常规综合治疗方法,观察组病人则在常规综合治疗方法基础上加用乌司他丁辅助治疗。治疗后对两组病人的肺功能和炎性因子,胸CT,胸片等多项临床指标进行分析。结果:观察组病人治疗后血气分析结果明显好于对照组(均P<0.05);观察组病人治疗前以及48小时后其白细胞介素8、白细胞介素6、肿瘤坏死因子α、等炎性因子指标水平明显低于对照组(均P<0.05);观察组病人转化为急性呼吸窘迫综合征、气管插管呼吸机治疗以及死亡人数均低于对照组(均P<0.05);观察组病人在治疗一周后胸CT,胸片结果比较好于对照组(均P<0.05)。结论:对急性肺损伤病人运用乌司他丁辅助治疗可明显改善肺功能,降低炎症介质水平,改善病人预后。
To investigate the effect of ulinastatin on acute lung injury.Methods：80 cases of patients with acute lung injury by digital table method were randomly divided into observation group （40cases） and control group （40 cases）. The control group conventional treatment, the observation group in the conventional treatment based on the method of using ulinastatin treatment. After the treatment of two patients with pulmonary function and inlfammatory factor analysis.Results：The observation group after treatment, blood gas analysis results signiifcantly better than the control group （allP〈0.05）; observation of 48 h after tumor necrosis factor, interleukin 6, interleukin 8 and other inlfammatory factor levels in treatment group was signiifcantly lower than control group （allP〈0.05）; observation group the patient into acute respiratory distress syndrome, breathing and death cases were lower than the control group （allP〈0.05）;patients in the observation group after treatment in chest X-ray results in better than the control group （P〈0.05）.Conclusion： Treatment can signiifcantly improve lung function in patients on acute lung injury patients by Ulinastatin, improve the prognosis of the patients.
出处
《中国医药导刊》
2014年第8期1226-1227,1230,共3页
Chinese Journal of Medicinal Guide
