摘要
目的探讨短程糖皮质激素治疗慢性阻塞性肺疾病急性加重的临床疗效。方法选取2013年1月~2014年6月收治的慢性阻塞性肺疾病急性加重患者70例,随机分为两组,对照组给予标准糖皮质激素治疗,观察组给予短程糖皮质激素治疗。比较两组患者治疗前后的肺功能、动脉血气变化,以及治疗成功率、餐后2 h血糖水平。结果观察组治疗后血气改善情况显著优于对照组,组间差异具有统计学意义（P〈0.05）;观察组患者餐后2 h血糖水平明显比对照组低（P〈0.05）;两组在治疗成功率和肺功能改善情况上差异无统计学意义（P〉0.05）。结论应用短程糖皮质激素治疗慢性阻塞性肺疾病急性加重具有较高的临床效果,能显著改善患者的动脉血气情况看,且安全高效。
Objective To evaluate the clinical efficacy of short-systemic corticosteroids for patients with acute exacerbation of chronic obstructive pulmonary disease. Methods 70 cases of patients with acute exacerbation of chronic obstructive pulmonary disease were randomly divided into two groups. The control group were treated with standard hormone, while the observation group were treated with short systemic corticosteroids. Lung function（FRV1%pred）,arterial blood gas changes before and after treatment（Pa O2/Pa CO2/p H）, the success rate of treatment, 2 h postprandial blood glucose levels of two groups were compared. Results Pa O2/Pa CO2/p H improvement after treatment in the observation group was significantly better than that in the control group（P〈0.05）;2 h postprandial blood glucose levels in the the observation group was significantly lower than the control group（P〈0.05）;The success rate of treatment and lung function improvement in the two groups were no significant difference（P〉0.05）.Conclusion Application short systemic corticosteroids in chronic obstructive pulmonary disease has high clinical effect, which can significantly improve the patient＇s blood gas analysis, and be safe for patients.
出处
《中国处方药》
2015年第4期10-11,共2页
Journal of China Prescription Drug
关键词
糖皮质激素
慢性阻塞性肺疾病
急性加重
短程疗法
Systemic corticosteroids
Chronic obstructive pulmonary disease
Acute exacerbation
Short-term therapy
