摘要
目的探讨孕妇妊娠早期使用抗菌药物治疗生殖道感染的疗效以及与其早产之间的关系,降低早产的发生率。方法 2012年1月-2014年1月150例孕早期生殖道感染孕妇根据是否同意进行临床药物治疗分为干预组和对照组,干预组孕妇92例,对照组孕妇58例,干预组根据生殖道分泌物的检测结果使用抗菌药物治疗,对照组采取非药物治疗措施,对比两组孕妇生殖道感染的治愈率、早产率和分娩后3个月的产妇生活质量。结果干预组孕妇生殖道感染治愈率为90.2%,显著高于对照组的56.9%;干预组孕妇的早产率为3.3%,显著低于对照组的19.0%;分娩后3个月干预组产妇的生活质量4个维度的得分情况显著高于对照组,差异均有统计学意义(P<0.05)。结论孕妇20孕周之前使用抗菌药物治疗生殖道感染治疗效果好,有助于降低早产的发生率,改善孕妇的生活质量。
OBJECTIVE To explore the effect of use of antibiotics in early pregnancy on treatment of genital tract infections and observe its relationship with the preterm birth so as to reduce the incidence of preterm birth.METHODS From Jan 2012 to Jan 2014,a total of 150 pregnant women with genital tract infections in early pregnancy were recruited as the study objects and divided into the intervention group and the control group according to their willingness to receive clinical drug therapy,with 92 cases in the intervention group,58 cases in the control group.The intervention group was treated with antibiotics based on the results of detection of the genital tract secretions,while the control group was given the non-drug therapy;the cure rate of genital tract infections,rate of preterm birth,and quality of life of the pregnant women three months after delivery were observed and compared between the two groups.RESULTS The cure rate of genital tract infections of the intervention group was 90.2%,significantly higher than 56.9% of the control group;the rate of preterm birth of the intervention group was3.3%,lower than 19.0% of control group.Three months after the delivery,the scores of 4dimensions life quality of the intervention group was significantly higher than that of the control group（P〈0.05）.CONCLUSIONThe use of antibiotics within 20 gestational weeks can achieve significant effect on treatment of the genital tract infections,contribute to the reduction of incidence of preterm birth,and improve the quality of life of the pregnant women.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2015年第8期1876-1878,共3页
Chinese Journal of Nosocomiology
基金
重庆市基本科研基金资助项目(2014csct-jbky-01705)
关键词
妊娠早期
抗菌药物
生殖道感染
早产
Early pregnancy
Antibiotic
Genital tract infection
Preterm birth
