摘要
目的:观察米非司酮联合甲氨蝶呤用于保守治疗宫外孕的疗效,并探究其应用价值和临床意义。方法:选取2008年6月至2012年5月来我院接受治疗的100例宫外孕患者,将其随机分为联合治疗组和常规治疗组,每组50例。两组的治疗结束后,分析对比两组患者的治疗效果。结果:常规治疗组患者在腹痛、阴道流血、包块失血以及β-HCG指标恢复用时明显高于联合治疗组,联合治疗组患者承受的痛苦强度和承受痛苦的时间明显少于常规治疗组,联合治疗组的不良反应发生率明显少于常规治疗组,两组差异有统计学意义(P<0.05)。结论:米非司酮联合甲氨蝶呤用于保守治疗宫外孕的疗效显著,可有效缓解患者疼痛,缩短患者病痛时间,提高宫外孕的治愈率,减少不良反应的发生,值得在临床医学上广泛推广。
Objectives： To investigate the efficacy of mifepristone in combination with methotrexate for conservative treatment of ectopic pregnancy,and to explore its value and significance. Methods： 100 ectopic pregnancy patients in our hospital from June 2008 to May 2012 were randomly divided into combined treatment group and conventional treatment group,50 cases in each group. After treatment,the clinical efficiency of the two groups was compared. Results： For patients in the conventional treatment group,the abdominal pain,vaginal bleeding,hemorrhagic mass and time of β- HCG index recovery were significantly higher than the combined treatment group; the pains patients of combined treatment group suffered was longer and stronger than that of the conventional treatment group; the incidence of adverse reactions in the combined treatment group was significantly less than conventional treatment group,with statistically significant difference（ P〈 0. 05）. Conclusion： The efficacy of mifepristone in combination with methotrexate for conservative treatment of ectopic pregnancy is significant,which can effectively relieve and reduce pain in patients,improve the cure rate of ectopic pregnancy,and reduce the incidence of adverse reactions,thusly worth widely application in clinical.
出处
《中国性科学》
2015年第4期109-112,共4页
Chinese Journal of Human Sexuality
关键词
米非司酮
甲氨蝶呤
联合
保守治疗
宫外孕
Mifepristone
Methotrexate
Combined use
Conservative treatment
Ectopic pregnancy
