摘要
目的探讨高危人群中氯胺酮相关性膀胱炎的发病情况及流行病学特征。方法对强制戒毒所在押人员及招募长期单一吸食氯胺酮人群,采用自行改良设计的"药物滥用调查表",对调查对象的一般情况及相关下尿路症状等进行问卷调查。结果共调查837人,其中单一吸食氯胺酮人群有效分析问卷199份,高危人群中氯胺酮相关性膀胱炎的发病率25.63%。其中人口学特征如:年龄、婚姻、学历、收入等与发病率无相关性,差异无统计学意义;吸食时间、每次吸食量、每日吸食量和初次吸食年龄调查对象间的发病率比较发现,其差异亦均无统计学意义。多因素Logistic逐步回归分析表明,每日吸食≤2次vs.≥3次是氯胺酮相关性膀胱炎发生的危险性因素。结论每日吸食的次数是患病的危险因素,选择合适的干预及治疗方案可以有效的控制氯胺酮相关性膀胱炎的发生。
Objective To investigate the prevalence and epidemiological features of ketamine-associated cystitis in the high-risk group and to provide information for its prevention and treatment .Methods Detainees at the Second Compulsory Rehabilitation Center of Shenzhen City were surveyed with modified Drug Abuse Questionnaires during Jan .2012 and Dec . 2013 to collect data on the detainees’ general conditions and symptoms of lower urinary tract .Results A total of 837 individ-uals took part in the survey and 199 questionnaires collected were valid .The incidence of ketamine-associated cystitis of the high-risk group was 25 .63% ,which had no correlation with age ,marriage status ,education ,income ,period of drug abuse , dosage per time ,dosage per day ,and age of initial drug use （P〉0 .05） .Logistic regression analysis showed that the frequency of drug use per day （2-3 times a day） was a risk factor of ketamine-associated cystitis .Conclusion The frequency of daily drug use is a risk factor for ketamine-associated cystitis for the high-risk population .A reasonable plan of interference and treatment is effective to control the occurrence of ketamine-associated cystitis .
出处
《现代泌尿外科杂志》
CAS
2015年第4期225-228,共4页
Journal of Modern Urology
基金
2013年深圳市科技计划项目(No.201303260)
关键词
氯胺酮
膀胱炎
下尿路症状
流行病学调查
ketamine
cystitis
lower urinary tract symptom
epidemiological investigation
