摘要
目的:观察肥儿合剂治疗脾胃不和型小儿厌食症对血清瘦素(LEP)、血浆胆囊收缩素(CCK)水平的影响。方法:选择符合脾胃不和型小儿厌食症诊断标准的患儿60例,随机分为肥儿合剂治疗组、复方消化酶胶囊对照组各30例,观察两组治疗前后LEP、CCK含量,证候积分变化及综合疗效。结果:治疗后,治疗组综合疗效明显优于对照组(P<0.01);证候总积分变化治疗组优于对照组(P<0.05);两组血清LEP含量及血浆CCK含量治疗前后比较均有显著性差异(P<0.01),两组治疗后血清LEP含量升高水平相当(P>0.05),治疗组治疗后血浆CCK含量低于对照组(P<0.05)。结论:肥儿合剂可有效改善患儿厌食症状,能通过调节厌食症患儿血清LEP和血浆CCK水平对食欲产生影响。
Objective：To observe the effect of Feier mixtures on serum leptin and cholecystokinin level of child anorexia of disharmony between spleen and stomach type. Methods：60 children who met the diagnosis standard of child anorexia of disharmony between spleen and stomach type were randomly divided into two groups：Feier Mixtures group and compound digestive enzyme capsule group. Each group had 30 children.The changes of serum leptin,cholecystokinin,scores of symptoms and signs,and comprehesive curative effect of the two groups after the treatment were observed. Results：After treatment,the curative effect of Feier Mixtures group was superior to compound digestive enzyme capsule group（P〈 0.01）. The level of plasma CCK and serum leptin of the two groups after treatment were significantly different from that before treatment（P 〈0.01）. There were no significant differences in the effect on raising serum leptin level of the two medicines（P 〉0.05）. The effect on lowering plasma CCK level of Feier Mixtures was superior to that of compound digestive enzyme capsule（P 〈0.05）. Conclusion：Feier Mixtures can effectively improve the symp toms of anorexia. It acted on appetite by regulating the level of plasma CCK and serum leptin.
出处
《山东中医药大学学报》
2015年第2期127-129,共3页
Journal of Shandong University of Traditional Chinese Medicine
基金
浙江省中医药科技计划项目(编号:2012ZB153)
关键词
小儿厌食症
脾胃不和型
肥儿合剂
瘦素
胆囊收缩素
child anorexia
type of disharmony between spleen and stomach
feier mixtures
serum leptin
cholecystokinin
