摘要
目的:探讨肾康注射液与前列地尔(曼新妥)联合应用治疗糖尿病肾病(DN)的疗效方法:随机将60例DN患者分为三组:A组肾康注射液组(20例)、B组前列地尔组(20例)和C组肾康注射液列地尔联合治疗组(20例),A组0.9%氯化钠溶液250ml+肾康注射液60ml,B组0.9%氯化钠溶液100ml+前列地尔10μg,C组肾康注射液与前列地尔联合应用,三组均1次/d,连用14 d。结果:治疗后三组患者的BUN、Cr、24 h尿蛋白、TC、TG的检测值均低于治疗前,C组患者各项指标显著低于治疗A、B组(P<0.05或P<0.01)。结论:肾康注射液及前列地尔注射液均可改善糖尿病肾病的临床指标,且两者联合使用效果更为明显。
Objective: To observe the effect of Alprostadil injection combined with Shenkang injection in the treatment of diabetic nephropathy. Methods: 60 patients with diabetic nephropathy were randomly divided into Alprostadil group(20 case) Shenkang group(20 cases) and combined treatment group(20 eases). The A group was given Shenkang injection 60ml and The B group was given Alprostadil injection(101xg/day), The combined treatment group was given Alprostadil injection( 10μg,once/day) and Shenkang injection (60ml,once/day). The course of treatment was two weeks. Results: The levels ofTC, TG, Cr, BUN, 24- hour urine protein in the three groups showed significantly turn better than before (p〈0.05), patients in the combined treatment have the best performance in three group. (p〈0.05) Conclusion: Combine treatment of Alprostadil injection and Shenkang injection have strong effective in the treatment of diabetic nephropathy.
出处
《中国医学装备》
2014年第B12期234-234,共1页
China Medical Equipment
关键词
肾康注射液
前列地尔
糖尿病肾病
Shenkang injection
Alprostadil
Diabetic Nephropathy