摘要
目的观察转移性乳腺癌经过化疗后应用卡培他滨维持治疗的效果。方法 34例转移性乳腺癌患者应用常规化疗后分为治疗组和未治疗组,各17例。治疗组口服卡培他滨2500 mg/m2,14 d,每21天1个周期。治疗2个周期后开始评价疗效。结果随访治疗组的中位疾病进展时间(11个月)长于未治疗组(8个月),两组差异有统计学意义(P<0.05)。结论卡培他滨用于转移性乳腺癌化疗后维持治疗能延缓疾病进展时间。
Objective To observe the curative effect of capecitabine in maintenance treatment of metastatic breast cancer after chemotherapy. Methods A total of 34 patients with metastatic breast cancer after chemotherapy were divided into treatment group and non-treatment group with 17 cases in each group. The treatment group received oral administration of 2500 mg/m2 of capecitabine for 14 d. Every 21 days were taken as 1 treatment course. Curative effect was evaluated after 2 treatment courses. Results The median progression time of the treatment group(11 months) was longer than the non-treatment group(8 months), and the difference had statistical significance(P〈0.05). Conclusion Capecitabine can suspend progression time in maintenance treatment of metastatic breast cancer after chemotherapy.
出处
《中国实用医药》
2015年第7期31-32,共2页
China Practical Medicine
关键词
转移性乳腺癌
卡培他滨
维持治疗
Metastatic breast cancer
Capecitabine
Maintenance treatment