摘要
现代辅助生殖技术(ART)中,子宫内膜容受性受损成为限制胚胎成功种植的重要因素之一。如何合理评价子宫内膜容受性一直是临床和基础研究关心的问题。本文主要综述目前用于评估子宫内膜容受性的临床指标,形态学、分子标志物,以及最新的蛋白组学评估方法,并分析其应用价值,以期提供更好、更客观和实时的子宫内膜容受性的评价指标,进而更加有的放矢地治疗不孕症患者,最大可能提高ART妊娠率。
In modem assisted reproductive technology （ART）, impaired endometrial receptivity might be one of the major limiting factors for a successful implantation of embryos. How to evaluate endometrial receptivity reasonably has been a focused issue by both clinical and basic research. This paper mainly reviewed some evaluation markers of endometrial receptivity, including clinic index, morphological features, biomarkers, and the latest proteomics method. In addition, we will analyze the practical value, in order to provide more reasonable, objective and real-time index to assess endometrial receptivity, and thus a more targeted and personal treatment of infertility patients, and finally increase pregnancy rate of ART.
出处
《生殖与避孕》
CAS
CSCD
北大核心
2015年第4期271-276,共6页
Reproduction and Contraception
