摘要
目的:探讨纤维结肠镜检在儿童抗生素相关腹泻病(AAD)诊断及鉴别诊断中的意义。方法:对18例临床确诊抗生素相关腹泻患儿采用非麻醉方法行纤维结肠镜检查。结果:18例AAD儿童结肠镜下表现为结肠黏膜呈弥漫性充血、水肿、血管分支模糊不清或消失14例,散在阿弗他溃疡,周围绕以红晕3例;散在的糜烂溃疡及出血1例,未见假膜性肠炎表现。病变部位:乙状结肠及直肠9例,结肠脾曲及降结肠2例,横结肠3例,结肠肝曲及升结肠4例。18例患儿均行结肠黏膜活检,镜下为非特异性炎性变化。结论:儿童抗生素相关腹泻结肠镜表现均为非特异性炎性变化,较成人AAD镜下表现轻。儿童纤维结肠镜检查安全、快速、在儿童AAD的诊断及鉴别诊断中有十分重要的作用,值得应用及推广。
Objective：To observe the changes of the gastrointestinal tract of antibiotic-associated diarrhea（AAD）under fiber colonoscopy and differential diagnosis of AAD in children.Methods：Eighteen cases of AAD in our hospital were diagnosed by fiber colonoscopy examination.Results：Eighteen cases of AAD children colonoscopy showed colonic mucosa presenting diffuse edema,vascular branching blurred or disappeared in 14 cases,3cases showed scattered aphthous ulcers with flush around.Scattered debaucjed ulcer and bleeding were found in 1case,with no pseudomembranous colitis performance.Lesions were found in the sigmoid colon and rectum appeared in nine cases,splenic flexure and descending colon in 2cases,transverse colon in 3cases,hepatic flexure of colon and ascending colon in 4cases.All 18 cases of children underwent colonic mucosa biopsy,with non-specific inflammatory changes.Conclusion：The performance of colonoscopy in AAD of children has non-specific inflammatory changes.Colonoscopy is safe and fast which plays a very important role in the diagnosis and differential diagnosis of AAD in children.
出处
《武汉大学学报（医学版）》
CAS
2015年第3期432-433,450,共3页
Medical Journal of Wuhan University
基金
湖北省自然科学基金项目(编号:2009CDZ021)
关键词
纤维结肠镜检
抗生素相关腹泻
儿童
Fiber Colonoscopy
Antibiotic-Associated Diarrhea Children
