摘要
最新研究表明,肠道菌群与代谢综合征关系密切,与其重要的靶器官心血管系统关系尤为显著。肠道菌群对胆固醇、胆汁酸的代谢直接影响血中胆固醇的水平,同时胆固醇的水平又是动脉粥样硬化形成的关键环节。本文主要对肠道菌群依赖性代谢产物氧化三甲胺(trimetlylamine oxide,TMAO)与心血管疾病发病的根源动脉粥样硬化的关系进行综述。
Recent researches revealed that intestinal flora contribute to the development of metabolic syndrome, espe？cially to the disorder of their targeted cardiovascular system. Blood cholesterol level is affected by the metabolism of intesti？nal flora in cholesterol and bile acid. At the same time, the blood cholesterol level is the key player in development of athero？sclerosis. This review mainly discussed the relationship between the intestinal flora dependent metabolite trimethylamine ox？ide （Trimetlylamine oxide, TMAO） and atherosclerosis.
出处
《天津医药》
CAS
2015年第4期443-445,共3页
Tianjin Medical Journal
关键词
动脉粥样硬化
代谢综合征X
肠杆菌科
心血管疾病
胆固醇
氧化三甲胺
atherosclerosis
metabolic syndrome X
enterobacteriaceae
cardiovascular diseases
cholesterol
trimetlyl-amine oxide
