摘要
卵巢癌患者的静脉血栓发生率远高于其他妇科肿瘤,约20%以上的卵巢癌患者存在高凝状态。肿瘤可导致血液高凝状态,而凝血功能的过度激活也极大地促进肿瘤的进展,是影响患者预后的重要因素。近年来,高凝状态逐渐成为卵巢癌研究领域的新热点,本文将对卵巢癌患者高凝状态的形成机制、临床意义及相关治疗进展进行综述。
The incidence of venous thromboembolism in patients with ovarian cancer is much higher than other gynecologic cancers. Approximate 20%of ovarian cancer patients have hypercoagulable status during different phases of their disease. Ovarian cancer itself can induce hypercoagulability, but meanwhile the over activated coagulation system may promote disease progression. Coagulation system disorder is one of the most important prognostic factors in ovarian cancer. Recently, hypercoagulability becomes a hot spot in the ovarian cancer research ifeld. This article reviews the mechanism of hypercoagulability, its clinical implication and correlated treatment in ovarian cancer patients.
出处
《中国癌症杂志》
CAS
CSCD
北大核心
2015年第3期231-234,共4页
China Oncology
基金
上海市科学技术委员会重点项目(12411950300)
