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脂肪滋养蛋白Ⅰ1484M基因多态性与肝细胞癌关系的研究进展 被引量:1

Polymorphisms in the PNPLA3 gene are associated with hepatocellular carcinoma
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摘要 肝细胞性肝癌(HCC)是临床常见的恶性肿瘤之一,位于全球恶性肿瘤死因的第3位[1]。慢性病毒感染、酒精性肝病、年龄、性别、糖尿病、家族史和种族等均与其发生和发展相关,是多因素、多基因突变的复杂病变过程。HCC早期诊断困难,生存期短,在美国和欧洲国家,其发病率增加很大程度上是由当前流行的丙型肝炎病毒感染所致;
出处 《中华肝脏病杂志》 CAS CSCD 北大核心 2015年第4期310-314,共5页 Chinese Journal of Hepatology
关键词 肝细胞 多态性 寡核苷酸 Carcinoma, hepatocellttlar Polymorphism, singlenucleotide
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参考文献29

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