摘要
G蛋白偶联雌激素受体(GPER)是上世纪90年代发现的一种新型的雌激素受体,它可以独立于经典的雌激素核受体介导雌激素的多种生物学功能。GPER可通过激活EGFR和c AMP介导雌激素的快速非基因组效应,GPER还可与其它多个信号转导通路进行对话。因此,本文就GPER信号转导通路作以综述。
G protein-coupled estrogen receptor（GPER） is a novel estrogen receptor found in 1990s, can meditate multiple estrogen function independent of the classic estrogen receptors. GPER can mediate the rapid nongenomic effects of estrogen by activating EGFR and cAMP. GPRE can also talk cross with multiple signal transduction pathways. In the present article, the GPER signal transduction pathways are reviewed.
出处
《解剖科学进展》
CAS
2015年第2期211-213,215,共4页
Progress of Anatomical Sciences
基金
黑龙江省归国留学基金项目(No.LC2013C06)
