摘要
目的分析手术患者麻醉后下呼吸道感染的病原菌及其耐药性,对临床预防和治疗麻醉后下呼吸道感染提供参考依据。方法选取2010年3月-2013年11月麻醉后发生下呼吸道感染的患者共122例,取其深部痰液标本,进行分离培养,并利用K-B琼脂法对病原菌的耐药性进行药敏试验,数据采用SPSS 17.0软件进行统计处理。结果 122例发生麻醉后下呼吸道感染的患者中以采用全麻导致感染为主,共48例占39.34%;共分离革兰阳性菌56株占43.75%,革兰阴性菌72株占56.25%;感染主要革兰阳性菌对利奈唑胺、多西环素和加替沙星的耐药率较低,均<10.00%;麻醉后下呼吸道感染的主要革兰阴性菌对亚胺培南、多黏菌素和替考拉宁的耐药率较低,均<10.00%。结论患者麻醉后下呼吸道感染的病原菌多具有耐药性,临床发生麻醉后下呼吸道感染时,应先分离培养病原菌并进行耐药试验,选择耐药率低的抗菌药物进行治疗。
OBJECTIVE To analyze the pathogenic bacteria and their drug resistance in patients with lower respiratory tract infections after anesthesia,and provide some reference for prevention and treatment of lower respiratory tract infections after anesthesia.METHODS Totally 122 cases of patients with lower respiratory tract infections after anesthesia were chosen,pathogenic bacteria were isolated and cultured from sputum specimens collected from the deep section,drug resistance test was performed by K-B test.Data were statistically analyzed by the software SPSS17.0.RESULTS General anesthesia in 48 patients accounted for 39.34%,being the largest proportion of 122 patients with lower respiratory tract infections after anesthesia.Totally 56 strains of gram-positive bacteria were detected,accounting for 43.75% and 72 strains of gram-negative bacteria were detected,accounting for 56.25%.Gram-positive bacteria had a low resistance of〈10.00%to linezolid,doxycycline and gatifloxacin,gram-negative bacteria had a low resistance of〈10.00% to imipenem,polymyxin and teicoplanin.CONCLUSION Pathogenic bacteria have certain resistance to common antibiotics.When infections occurred,pathogenic bacterial types should be distinguished and antimicrobial drugs with low resistance rates should be chosen to treat patients.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2015年第7期1596-1598,共3页
Chinese Journal of Nosocomiology
基金
滨州市科技局基金资助项目(JB[S]2013-4-2-4)
关键词
麻醉
下呼吸道
感染
分析
Anesthesia
Lower respiratory tract
Infections
Analysis
