摘要
目的评估在新生儿脓毒症诊断时,PCT与C反应蛋白(CRP)、白细胞(WBC)计数相比所占的特殊优势。方法搜集2013年1月至2014年1月在辽宁省大连市中心医院的新生儿科住院的新生儿脓毒症的患儿46例,另选取50例同期住院非患新生儿脓毒症的新生儿作为对照组,入院时均做PCT,CRP和WBC计数检查。结果两组WBC计数比较差异无统计学意义(P>0.05),但PCT、CRP检查差异均有统计学意义(P<0.01),其中PCT诊断新生儿脓毒症的灵敏度(87%)明显高于CRP(63%),但是特异性(88%)略低于CRP(94%)。PCT约登指数明显高于CRP和WBC计数。结论 PCT在新生儿脓毒症诊断中优于CRP和WBC计数。
Objective To determine the special diagnostic superiority of PCT test over CRP and WBC count test for neonatal sepsis.Methods 46 newborn inpatients diagnosed neonatal sepsis in the neonatal department of Dalian Central Hospital from January 2013 to January 2014 and contemporaneous 50 uninfected neonatal inpatients as control group were collected.The PCT and CRP concentrations and WBC count were simultaneously measured at admission.Results The WBC count had no statistical difference between the two groups,but the PCT and CRP detection showed the statistical difference between the two groups（P〈0.01）,the sensitivity of PCT test was 87%,which was significantly higher than 63% of CRP test,but the specificity of PCT test was 87%,which was slightly lower than 90% of CRP test.The Youden index of PCT test was obviously higher than that of CRP test and WBC count.Conclusion PCT is superior to CRP and WBC count in diagnosing neonatal sepsis.
出处
《国际检验医学杂志》
CAS
2015年第7期913-914,917,共3页
International Journal of Laboratory Medicine
