摘要
目的 汇总分析超声造影诊断肾脏肿瘤的中英文文献,评价超声造影对肾脏肿瘤的诊断价值。资料与方法 以超声造影、肾脏肿瘤为主题词,检索中国知网（CNKI）、万方数据库、中国生物医学文献光盘数据库（CBMDisc）、维普数据库、Embase、Cochrane图书馆和PubMed数据库,检索时间为2009年3月—2014年3月。按照循证医学要求,对符合纳入标准和排除标准的文献进行异质性检验和文献质量评价。计算纳入文献的合并敏感度、特异度、诊断比值比,绘制受试者工作特征曲线（SROC）,并计算曲线下面积（AUC）和Q指数。结果 共有12篇文献符合纳入标准,其中中文文献9篇,英文文献3篇。文献异质性较低,采用固定效应模型汇总加权得到合并敏感度为0.95（95%CI 0.93~0.96）、特异度为0.79（95%CI0.73~0.84）、诊断比值比为76.36（95%CI 41.73~139.71）、Q指数为0.9208、SROCAUC为0.9706。结论 超声造影对肾脏肿瘤有着较高的诊断价值和准确度,可以为临床决策提供影像学依据。
Purpose To review English and Chinese literatures on diagnosing kidney tumor using contrast enhanced ultrasound （CEUS）. Materials and Methods CEUS and kidney tumor were selected as the key words to search CNKI, Wanfang data, CBMDisc, VIP, Embase, the Cochrane Library and PubMed from March 2009 to March 2014. According to evidence-based medicine requirements, heterogeneity test and quality evaluation were performed to evaluate the literature that met the inclusion criteria. The pooled sensitivity, specificity and diagnostic odds ratio （DOR） of included literature were calculated to determine summery receiver operating characteristic curve （SROC）, and calculated the area under the curve （AUC） as well as Q index. Results A total of 12 studies met the inclusion criteria, including 9 in Chinese and 3 in English. Heterogeneity test showed a low heterogeneity among the literature, thus fixed effect models used. The pooled sensitivity was 0.95 （95% CI 0.93-0.96）, specificity was 0.79 （95% CI 0.73-0.84）, DOR was 76.36 （95% CI41.73-139.71）, Q index was 0.9208, and SROC AUC was 0.9706. Conclusion CEUS has high diagnostic value and accuracy for kidney tumors, which can provide imaging information for clinical decision.
出处
《中国医学影像学杂志》
CSCD
北大核心
2015年第1期41-44,共4页
Chinese Journal of Medical Imaging
基金
辽宁省自然科学基金项目(2014021051)
关键词
肾肿瘤
超声检查
超声造影
META分析
Kidney neoplasms
Ultrasonography
Contrast-enhanced ultrasound
Metaanalysis
