期刊文献+

乳腺癌患者血清内中期因子表达及临床意义 被引量:1

下载PDF
导出
摘要 目的探究乳腺癌患者血清内中期因子表达及其临床意义。方法随机选取2010年3月至2014年3月收治的的腺疾病患者150例,其中75例经诊断为乳腺癌(乳腺癌组),75例为乳腺良性疾病(乳腺良性疾病组)。2组患者均在入院后取血样,采取ELISA法测定血清中期因子(MK)浓度。记录MK含量并计算阳性率,分析各临床指标与MK含量的关系。结果乳腺癌组,患者术前MK含量为(738±103)pg/ml,阳性率为85.3%;乳腺良性疾病组,患者术前MK含量为(471±97)pg/ml,阳性率为6.7%,2组阳性率比较,差异有统计学意义(P<0.05)。在各指标MK阳性率的比较中,各临床分期相比、两类肿瘤大小相比、淋巴结转移与否相比,差异有统计学意义(P<0.05)。而2年龄段人群MK阳性率进行比较,差异无统计学意义(P>0.05)。结论乳腺癌患者血清中中期因子具有较高的表达,检测其含量对判断疾病的临床分期、严重程度,作出临床诊断及预后均具有重大意义。
作者 杨旦 沈祥
出处 《河北医药》 CAS 2015年第8期1174-1176,共3页 Hebei Medical Journal
  • 相关文献

参考文献3

二级参考文献16

  • 1杨玲,李连弟,陈育德,D.M.Parkin.中国乳腺癌发病死亡趋势的估计与预测[J].中华肿瘤杂志,2006,28(6):438-440. 被引量:278
  • 2Li-cheng DAI,Xiang WANG,Xing YAO,Li-shan MIN,Jin-liang PING,Jian-fang HE.Antisense oligonucleotides targeting midkine inhibit tumor growth in an in situ human hepatocellular carcinoma model[J].Acta Pharmacologica Sinica,2007,28(3):453-457. 被引量:20
  • 3Li-Cheng Dai,Xiang Wang,Xing Yao,Yong-Liang Lu,Jin-Liang Ping,Jian-Fang He.Antisense oligonucleotide targeting midkine suppresses in vivo angiogenesis[J].World Journal of Gastroenterology,2007,13(8):1208-1213. 被引量:7
  • 4Anna Nordin,Wanzhong Wang,Karin Welén,Jan‐Erik Damber.Midkine is associated with neuroendocrine differentiation in castration‐resistant prostate cancer[J].Prostate.2012(6) 被引量:1
  • 5Güralp O. Ceyhan,Karl-Herbert Sch?fer,Annika G. Kerscher,Ulrich Rauch,Ihsan Ekin Demir,Mustafa Kadihasanoglu,Carolin B?hm,Michael W. Müller,Markus W. Büchler,Nathalia A. Giese,Mert Erkan,Helmut Friess.Nerve Growth Factor and Artemin Are Paracrine Mediators of Pancreatic Neuropathy in Pancreatic Adenocarcinoma[J].Annals of Surgery.2010(5) 被引量:2
  • 6Jun Yao,Qingyong Ma,Liancai Wang,Min Zhang.Pleiotrophin Expression in Human Pancreatic Cancer and Its Correlation with Clinicopathological Features, Perineural Invasion, and Prognosis[J].Digestive Diseases and Sciences.2009(4) 被引量:1
  • 7Seiji Ohhashi,Kenoki Ohuchida,Kazuhiro Mizumoto,Takuya Egami,Jun Yu,Lin Cui,Hiroki Toma,Shunichi Takahata,Toshinaga Nabae,Masao Tanaka.Midkine mRNA Is Overexpressed in Pancreatic Cancer[J].Digestive Diseases and Sciences.2009(4) 被引量:1
  • 8JunMa,YumeiJiang,YuhuaJiang,YanSun,XuemingZhao.Expression of nerve growth factor and tyrosine kinase receptor A and correlation with perineural invasion in pancreatic cancer[J].Journal of Gastroenterology and Hepatology.2008(12) 被引量:1
  • 9Güralp O. Ceyhan,Ihsan Ekin Demir,Burak Altintas,Ulrich Rauch,Gerald Thiel,Michael W. Müller,Nathalia A. Giese,Helmut Friess,Karl-Herbert Sch?fer.Neural invasion in pancreatic cancer: A mutual tropism between neurons and cancer cells[J].Biochemical and Biophysical Research Communications.2008(3) 被引量:2
  • 10Shuichi Mitsunaga,Takahiro Hasebe,Taira Kinoshita,Masaru Konishi,Shinichiro Takahashi,Naoto Gotohda,Toshio Nakagohri,Atsushi Ochiai.Detail Histologic Analysis of Nerve Plexus Invasion in Invasive Ductal Carcinoma of the Pancreas and Its Prognostic Impact[J].The American Journal of Surgical Pathology.2007(11) 被引量:1

共引文献18

同被引文献9

引证文献1

二级引证文献6

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部