摘要
目的：观察乳果糖对减少胆道结石患者胆道感染复发的疗效。方法：收治仅保守治疗的胆道结石并感染患者102例，根据随机原则分为治疗组（48例）和对照组（54例）。各组在达到缓解标准后，服用消炎利胆片（1.04g，3次/d），治疗组在此基础上加服乳果糖（10ml，1～3次/d），门诊治疗随访观察1年，缓解期间不予使用抗生素，观察并记录患者的复发次数及缓解时间。结果：治疗组的缓解天数明显长于对照组（P＜0.05），治疗组观察期间发作次数小于对照组（P＜0.05）。结论：口服乳果糖对减少胆道结石患者胆道感染的复发及延长缓解期有效。
Objective：To search the curative effect of Lactulose in reducing recurrence of biliary tract infection in biliary calculi patients. Methods：102 patients were randomLy to receive Inflammation-Resolving Gall-Bladder-Excreting Tablet （1.04g,tid）（54patients）or combined with Lactulose （10ml,qd-tid）（48patients）. All patients were followed up in outpatient clinic for 1 year without any antibiotics only if infection recurrence. The differences of the recurrence rate and the response duration were compared.Results：There were significantly lower recurrence rate and longer response duration in patients receiving combination drugs with Lactulose than control group （P〈0.05）. Conclusion：Lower recurrence rate and longer response duration in patients receiving combination drugs with Lactulose.
出处
《北方药学》
2015年第4期15-16,共2页
Journal of North Pharmacy
关键词
乳果糖
胆道结石
胆道感染
Lactulose Biliary calculi Biliary tract infection
