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三氯乙烯以及四氯乙烯室内空气污染与不良分娩结局的关系研究 被引量:1

Association Between Adverse Birth Outcomes and Indoor Air Pollution of Trichloroethylene and Tetrachloroethylene
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摘要 目的探讨三氯乙烯以及四氯乙烯室内空气污染与不良分娩结局的关系。方法选取深圳市坪山新区2008-12/2013-05接诊的暴露于三氯乙烯以及四氯乙烯室内空气污染的孕妇132例为观察组,根据分娩季节分为2组,在非采暖期分娩的孕妇94例为观察A组,在采暖期分娩的孕妇38例为观察B组,选取深圳市坪山新区同期接诊的未暴露于三氯乙烯以及四氯乙烯室内空气污染的孕妇128例为对照组,分析各组孕妇的分娩情况及胎儿情况。结果观察组胎儿体重、孕周均明显小于对照组,观察组早产儿发生率、低体重发生率均高于对照组,差异均有统计学意义(P<0.05)。观察组顺产率低于对照组,观察组心脏缺陷发生率、死胎发生率均高于对照组,观察B组顺产率明显低于观察A组,观察B组胎儿体重、孕周均小于观察A组,观察B组早产儿发生率、低体重发生率、心脏缺陷发生率、死胎发生率均高于观察A组,但差异均无统计学意义(P>0.05)。结论三氯乙烯以及四氯乙烯室内空气污染可造成不良分娩结局的发生,与季节无关。 Objective To explore the association between adverse birth outcomes and indoor air pollution of tri- chloroethylene and tetrachloroethylene. Methods A total of 132 pregnant women exposed to indoor air pollution of trichloroethylene or tetrachloroethylene were selected in Shenzhen Pingshan new district from December 2008 to May 2013 as observationgroup. According to breeding season, pregnant women were divided into two groups : 94 pregnant in non - heating period of delivery as observation A group and 38 pregnant women in heat- ing period of delivery as observation B group. Meanwhile, 128 pregnant women without exposure to indoor air pollution of trichloroethylene or tetrachloroethylene were selected at same period as control group. Delivery situ-ation and fetal situation were analyzed. Results Fetal weight and gestational weeks in observation group were significantly less than control group; incidences of pre- mature birth and low birth weight in observation group were both statistically higher than control group, all the difference were statistically significant ( all P 〈 0. 05 ). Rate of vaginal delivery in observation group was lower than that in control group; incidences of heart defect and stillbirth in observation group were both higher than that in control group; rate of vaginal delivery in obser- vation B group was lower than that in observation A group ; incidences of premature birth, low birth weight, heart defect, stillbirth in observation B group were all higher than that in observation A group; however, the aforementioned differences were not statistically significant (all P 〉 O. 05). Conclusion Indoor air pollution of trichloroethylene or tetrachloroethylene can cause adverse birth outcomes and is not associated with season.
出处 《预防医学情报杂志》 CAS 2015年第3期173-176,共4页 Journal of Preventive Medicine Information
基金 工作场所空气中甲缩醛检测方法研究与职业暴露情况调查(项目编号:深圳市龙岗区医疗卫生类科技项目ys2011011)
关键词 三氯乙烯 四氯乙烯 室内空气污染 不良分娩结局 trichloroethylene tetrachloroethylene indoor air pollution adverse birth outcome
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