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乳腺癌分子显像研究进展 被引量:1

Progress on molecular imaging of breast cancer
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摘要 随着我国女性乳腺癌发病率和病死率的上升,乳腺癌的早期诊断及其疗效评估显得非常重要。常规影像学检查,包括乳腺X射线摄影、超声、CT、MRI等,在乳腺癌的诊断和疗效监测方面发挥了非常重要的作用,但也表现出较大的局限性。分子影像学技术,特别是磁共振分子显像和PET分子显像,在乳腺癌的早期诊断和治疗指导方面发挥了独特的作用,可大幅度提高影像学诊断的准确率。笔者就目前乳腺癌磁共振分子影像学和PET分子影像学诊断的新进展进行综述。 As the incidence and the mortality rate of female breast cancer in our country is increasing in recent years, early diagnosis and therapeutic assessment of breast cancer are particularly important. Conventional imaging examinations including mammography, ultrasound, CT, and MRI, etc. have an important role in the early diagnosis and treatment evaluating of breast cancer management, however, they possess some limitations. Molecular imaging techniques, especially magnetic resonance molecular imaging and PET molecular imaging , enables the depiction of tumor morphology, as well as the assessment of functional and metabolic processes involved in cancer development at different levels, which can significantly improve imaging diagnosis accuracy. This review summarise the potential role and new progress of magnetic resonance molecular imaging and PET molecular imaging of emerging functional and metabolic processes as well as hormone receptors and growth factor receptors for diagnosis, predicting and monitoring treatment response in breast cancer patients.
出处 《国际放射医学核医学杂志》 2015年第1期91-95,共5页 International Journal of Radiation Medicine and Nuclear Medicine
基金 国家自然科学基金(81371584) 广州市科技计划对外合作项目(2011J5200025) 广东省科技计划项目(20138021800264)
关键词 乳腺肿瘤 磁共振成像 正电子发射断层显像术 体层摄影术 X线计算机 Breast neoplasms Magnetic resonance imaging Positron-emission tomography Tomography,X-ray computed
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