摘要
目的 探讨维吾尔族与汉族孕妇重度先兆子痫的临床特点及围生期结局.方法 对204例（维吾尔族145例,汉族59例）重度先兆子痫孕妇住院病例进行回顾性分析.比较维吾尔族与汉族孕妇重度先兆子痫发生率、一般情况、并发症、围生期结局等指标.结果 维吾尔族重度先兆子痫发生率高于汉族[7.7％（145/1 894）比3.8％ （59/1 549）],年龄小于汉族[（30±6）岁比（33±5）岁],差异均有统计学意义（P＜0.01或P＜0.05）.汉族孕妇终止妊娠的孕期为（34.23±0.28）周,维吾尔族孕妇为（33.75 ±0.52）周,差异无统计学意义（P＞0.05）.汉族孕妇平均血红蛋白水平为（106±24）g/L,维吾尔族孕妇为（108±21）g/L,差异无统计学意义（P＞0.05）.维吾尔族重度先兆子痫孕妇产检1～5次者所占比率高于汉族[44.1％（64/145）比23.7％（14/59）],差异有统计学意义（x2=17.388,P＜0.01）.与孕期产检≥5次者相比,产检1～5次孕妇患先兆子痫的风险增加3.276倍;未进行产检孕妇患先兆子痫的风险增加7.525倍;维吾尔族孕妇脏器损伤发生率高于汉族[18.6％ （27/145）比10.2％（6/59）],差异有统计学意义（P＜0.05）;维吾尔族孕妇胎儿窘迫、早产儿发生率高于汉族[37.9 ％（55/145）比27.1％（16/59）,20.7％（30/145）比10.2％ （6/59）],差异有统计学意义（P＜0.05）.结论 维吾尔族孕妇重度先兆子痫发生率明显高于汉族,加强产前检查可能降低维吾尔族孕妇重度先兆子痫的发生风险,并可能改善其母婴结局.
Objective To explore the clinical characteristics and perinatal outcomes of Uygur and Han pregnant women with severe preeclampsia. Methods Totally 204 pregnant women, including 145 Uygur pregnant women and 59 Han pregnant women with severe preeclampsia were retrospectively analyzed. The incidence of se- vere preeclampsia, general situation, complications and perinatal outcomes were compared between Uygur and Han patients. Results The incidence of severe preeclampsia was 7.7% （ 145/1 894） in Uygur women and 3.8% （59/1 549） in Han women（ P 〈 0.01 ）. The age of Han pregnant women with severe preeclampsia was higher than that of Uygur pregnant women with statistical difference [ （33 ± 5 ） years vs （30 ± 6） years, P 〈 0.051- No signif- icant difference in the gestational weeks of pregnancy termination was found between Han and Uygur pregnant women [ （34.23 ± 0.28） week vs （ 33.75 ± 0.52 ） week, P 〉 0.05 ], so was the level of hemoglobin [ （ 106 ± 24） g/L vs （ 108 ± 21 ） g/L, P 〉 0.05 ]. In Han pregnant women, 43 cases （72.9%） underwent ≥ 5 times of pregnancy check-up; 14 cases （23.7%） underwent 1-5 times of pregnancy check-up, and 2 cases （3.4%） did not undergo pregnancy check-up. While in Uygur pregnant women, 60 cases （41.4%） underwent /〉5 timesof pregnancy check-up, 64 cases （44.1%） underwent 1-5 times of pregnancy check-up, and 21 cases （ 14.5% ） did not undergo pregnancy check-up; the proportion of Uygur pregnant women undergoing 1-5 times of pregnancy check-up were significantly higher than that of Han pregnant women （X2 = 17. 388, P 〈 0.01 ）. The risk of pre- eclampsia increased by 3. 276 times among the pregnant women with 1-5 times of pregnancy check-up and by 7. 525 times among the pregnant women without pregnancy check-up, compared with that among the pregnant women with 〉15 times of pregnancy check-up. The incidence of organ damage in Uygur nationality was statistically higher than that in Han nationality（P 〈0.05） ;
出处
《中国医药》
2015年第4期559-561,共3页
China Medicine
基金
新疆维吾尔自治区人民医院院内科研项目（20120207）
关键词
重度先兆子痫
围生期
维吾尔族
汉族
Severe preeclampsia
Perinatal
Uygur nationality
Han nationality
