摘要
目的观察云南白药治疗新生儿重度窒息合并胃出血的临床效果。方法将2012年1月-2014年9月河北省石家庄市妇幼保健院收治的83例重度窒息合并胃出血新生儿,按住院号奇偶数分为治疗组43例,对照组40例。两组均积极治疗原发病,留置胃管,禁食,给予对症支持治疗。治疗组予交替鼻饲云南白药和磷酸铝凝胶,对照组仅予鼻饲云南白药。观察疗效及不良反应。结果治疗组总有效率为97.67%,对照组总有效率为82.50%,两组比较差异有统计学意义（P〈0.05）。治疗组停止呕血时间、胃内容物潜血转阴时间、停止排柏油样便时间分别为（3.77±1.43）、（43.91±16.88）、（8.77±2.11）h,对照组分别为（7.35±1.78）、（55.63±19.04）、（9.88±2.50）h,治疗组起效时间早于对照组,差异有统计学意义（P〈0.05或P〈0.01）。结论云南白药联合磷酸铝凝胶治疗新生儿重度窒息合并胃出血用药方便、经济,疗效确切,起效快,毒副作用小,值得临床推广。
Objective To investigate the curative effect of Yunnan Baiyao combined with Aluminum Phosphate Gel on severe neonatal asphyxia combined gastric bleeding. Methods Eighty three severely asphyxiated combined gastric bleeding full-term normal delivery newborn were selected in Shijiazhuang Maternal and Child Health Hospital from January 2012 to September 2014. They were divided into 43 cases of the therapy group and 40 cases of the control group according to the odevity of admission number. Two sets were all treated the primary disease and to detain the gastric tube, absolute diet, and other some supporting curation according to the clinical syndromes. The therapy group was nasal fed Yunnan Baiyao and Aluminum Phosphate Gel alternately. But the control group was only given Yunnan Baiyao. The curative effect was observed as well as untoward reaction. Results The effective power was 97.67% in the therapy group that super to 82.50% of the control group. There was a statistically significant difference（P〈0.05）. The time of stopping hematemesis, occult blood darkening in stomach contents and stopping row tarry stools between the therapy group and the control group was（3.77 ±1.43）,（43.91 ±16.88）,（8.77 ±2.11） h and（7.35 ±1.78）,（55.63 ±19.04）,（9.88 ±2.50） h respectively. Time of reaching valid was earlier than the control group（P〈0.05 or P〈0.01）.Conclusion Yunnan Baiyao combined with Aluminum Phosphate Gel on severe neonatal asphyxia combined gastric bleeding is convenient and economy on medication. The therapeutic effect is precise. Time of reaching valid is quick.And it has a diminutive toxic and side-effect. So it deserves clinical promotion.
出处
《中国医药导报》
CAS
2015年第7期86-88,92,共4页
China Medical Herald
基金
河北省科学技术研究与发展计划项目(编号122777147)
关键词
新生儿
窒息
胃出血
云南白药
磷酸铝凝胶
Neonates
Asphyxia
Gastric bleeding
Yunnan Baiyao
Aluminum Phosphate Gel
