摘要
目的：探讨阿托伐他汀辅助治疗冠心病高血脂的效果。方法选取2010年8月-2012年8月本院收治的94例冠心病高血脂患者作为研究对象，运用随机双盲法将其分为实验组（48例）和对照组（46例），对照组患者应用辛伐他汀治疗，实验组患者给予阿托伐他汀治疗。结果实验组的TC、TG、LDL-C、HDL-C等指标的改善情况明显优于对照组（P〈0.05）；实验组的血浆BNP含量明显低于对照组（P〈0.05）；两组的不良反应发生率差异无统计学意义（P〉0.05）。结论阿托伐他汀治疗冠心病高血脂能够有效降低患者的血脂，改善其临床症状，可在临床广泛推广。
Objective To investigate the effect of atorvastatin auxiliarily treating coronary heart disease and hyperlipi-demia. Methods From August 2010 to August 2012,94 cases with coronary heart disease and hyperlipidemia treated in our hospital were selected as study objects and they were divided into the experimental group （48 cases） and control group （46 cases） according to the randomized double blind method,the control group was treated with simvastatin,the experimental group was treated with atorvastatin. Results The Improvement of TC,TG,LDL-C and HDL-C index in the experimental group was significantly better than that in the control group （P〈0.05）;the content of BNP in the experi-mental group was significantly lower than that in the control group （P〈0.05）;there was no statistical difference of the in-cidence rate of adverse reaction in the two groups （P〉0.05）. Conclusion Atorvastatin auxiliarily treating coronary heart disease and hyperlipidemia can effectively reduce the blood lipid of patients,improve the clinical symptom of patients, and can be widely popularized in clinic.
出处
《中国当代医药》
2015年第7期132-133,138,共3页
China Modern Medicine
关键词
阿托伐他汀
辛伐他汀
药理
血脂
Atorvastatin
Simvastatin
Pharmacology
Blood lipid
